We evaluated the antimutagenic effects of 10 kinds of bioactive phytochemicals and some phytochemical combinations against methotrexate (MTX)-induced genotoxicity by the umu test in Salmonella typhimurium TA1535/pSK1002 combined with a micronucleus assay. We observed that allicin, proanthocyanidins, polyphenols, eleutherosides, and isoflavones had higher antimutagenic activities than the other ...

Garlic has long been used medicinally, most recently for its cardiovascular, antineoplastic, and antimicrobial properties. Sulfur compounds, including allicin, appear to be the active components in the root bulb of the garlic plant. Studies show significant but modest lipid-lowering effects and antiplatelet activity. Significant blood pressure reduction is not consistently noted. There is some ...

This article contains experimental data on the identification and quantification of the organosulfides on boiled garlic extracts. Data included are related to the research article "Boiling enriches the linear polysulfides and the hydrogen sulfide-releasing activity of garlic" (R. Tocmo, Y. Wu, D. Liang, V. Fogliano, D. Huang, 2016) [1]. Characterization was carried out by GC-MS and HPLC. Dose-r...

BACKGROUND Garlic has been suggested to lower blood pressure; however, studies evaluating this parameter have provided conflicting results. OBJECTIVE To examine the effect of garlic on blood pressure in patients with and without elevated systolic blood pressure (SPB) through meta-analyses of randomized controlled trials. METHODS A systematic search of MEDLINE, CINAHL, and the Cochrane Centr...

based on experiments showing immunomodulatory effects of garlic (allium sativum l.), we sought to see whether allium hirtifolim boiss., belonging to the same genus of garlic, has any effect on immune responses. hydroalcoholic extract and polyphenolic fraction of a. hirtifolium bulbs were prepared. allicin (diallyl thiosulfinate), a biologically active component, was identified in plant bulbs by...