previous studies have demonstrated some significant differences in hla allele frequencies in leukemic patients and normal subjects. we have analyzed hla class ii alleles and haplotypes in 60 iranian patients with acute myelogenous leukemia (aml) and 180 unrelated normal subjects. blood samples were collected after obtaining informed consents. from the patients and control dna extraction and hla...

The article presents the results of DNA genotyping sheep different breeds. It is first time polymorphism genes GH-HaeIII and CAST-MspI replacement breeds has been studied analyzed. testing identified specific features allele spectrum associated with meat production, expressed in frequencies occurrence both genotypes alleles. Carrier animals desirable alleles for breeding were gene loci under st...

asthma is a complex and multifactorial disorder. several studies have reported association between different hla- dqb1 and hla- drb1 alleles and allergic asthma. the aim of the present study was to investigate the association of hla-class ii alleles and haplotypes, with total serum ige and the results of the skin prick test in iranian children with allergic asthma. a total of 112 patients with ...

We characterized 549 new human leukocyte antigen (HLA) class I and class II alleles found in newly registered stem cell donors as a result of high-throughput HLA typing. New alleles include 101 HLA-A, 132 HLA-B, 105 HLA-C, 2 HLA-DRB1, 89 HLA-DQB1 and 120 HLA-DPB1 alleles. Mainly, new alleles comprised single nucleotide variations when compared with homologous sequences. We identified nonsynonym...

In yeast meiotic recombination, alleles used as genetic markers fall into two classes as regards their fate when incorporated into heteroduplex DNA. Normal alleles are those that form heteroduplexes that are nearly always recognized and corrected by the mismatch repair system operating in meiosis. High PMS (postmeiotic segregation) alleles form heteroduplexes that are inefficiently mismatch rep...

Low sequence divergence within functional alleles is predicted for the self-incompatibility locus because of strong negative frequency-dependent selection. Nevertheless, sequence variation within functional alleles is essential for current models of the evolution of new mating types. We genotyped the stylar self-incompatibility RNase of 20 Sorbus aucuparia from a population in the Pyrenees moun...

The results are presented from a simulation study of the spatial distribution of mutant alleles in a subdivided population. Statistical measures of the spatial pattern are defined in such a way that the same quantities could be measured in a geographic survey of allele frequencies in natural populations. Two types of quantities are discussed in this paper: (I) the occupancy distribution provide...

Sugarcane (Saccharum spp. hybrids) is one of the most important commercial crops for sugar, ethanol, and other byproducts production; therefore, it great significance to carry out genetic research. Assessing population structure diversity plays a vital role in managing resources gene mapping. In this study, we assessed among 196 Saccharum accessions, including 34 S. officinarum, 69 spontaneum, ...

In order to study the heritability and genetic parameters of antioxidant activity in barely (Hordeum vulgare L.) under salinity stress, a seven-parent half diallel (F1 crosses + parents) was conducted non-stress salt stress (8 12 dS m-1) conditions greenhouse, during 2016-17, Ardabil, Iran. this experiment, enzymes ascorbate peroxidase (APX), catalase (CAT) superoxide dismutase (SOD) were measu...

background: major histocompatibility complex (mhc) in chicken has profound influence on resistance/susceptibility to disease, and production and reproduction traits. microsatellite marker lei0258 is a genetic indicator for mhc haplotypes. recognizing diversity of mhc haplotypes in selectively bred populations will be helpful for selecting population resistant to disease and development of effec...