نتایج جستجو برای: alkylthio imidazole derivatives
تعداد نتایج: 111131 فیلتر نتایج به سال:
Nucleophilic carbenes have recently emerged as powerful 1,1-dipole equivalents for the construction of functionalized hydroindolone derivatives via a novel [4+1] cycloaddition with vinyl isocyanates in our laboratory. This methodology has been successfully used in the total synthesis of several alkaloids, such as tazettine and mesembrine. Currently, we are investigating the total synthesis of s...
Objective: Cancer is one of the major causes of death worldwide irrespective of the sex. The aim of the study was to design, synthesize, and identification of novel anti-proliferative agents that can potently target cancer. Methods: We are reporting the synthesis of the new series of N-substituted 2-(2-butyl-4-chloro-1H-imidazole-5-yl)-1H-benzo[d]imidazole derivatives and evaluated for their an...
In the present paper, we report on the synthesis, and in vitro antiviral and cytostatic activities of a series of novel imidazole[4,5-e][1,3]diazepine-4,8-dione (compounds 9-11) and acyclic carbamoyl imino-ureido imidazole (compounds 12 and 13) derivatives. These new type of chemical entities showed no significant activity on the broad spectrum of DNA and RNA viruses. Results of antiproliferati...
Fungicidal activity of widely used imidazole antifungal drugs in topical applications is not so strong in spite of their fungistatic activities against dermatophytes and pathogenic yeasts. In order to improve fungicidal activity of imidazole antifungal agents, a series of novel imidazole derivatives having a hydrophobic substituent derived from isoprenoid were synthesized. The efficacy of these...
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