Alkaloid caulerpin (1), along with β-sitosterol (2), were isolated from the n-hexane extract of macroalga Halimeda cylindracea Decaisne. The chemical structure was identified by a spectroscopic method including IR, MS, UV, NMR 1D, 2D, and comparison data spectra previously reported. Compounds (1) (2) for first time this macroalga. Compund evaluated their cytotoxicity activity against NCL-H460 l...

In the present study, the safety and toxicity of Dendrophthoe pentandra (DP) extracted using ethyl acetate were investigated. DP ethyl acetate (DPEA) extract was screened for its phytochemical constituents using standard procedure and active compounds present in DPEA extract were determined using gas chromatographymass spectrometry (GC-MS), the toxicity of DPEA extract was investigated using br...

Three novel furoquinoline alkaloid oxogeranyl ethers (1-3) and one known furoquinoline alkaloid (4) were isolated from the leaves of Boninia glabra, an endemic plant of the Bonin Islands. Their structures were elucidated on the basis of spectroscopic analysis.

Phytochemical screening and antifungal activity test of jengkol leaf (Archidendron jiringa) extract have been carried out. The purpose this research is determine secondary metabolite content activities extract. Extraction was conducted with sequential extraction technique various solvent such as hexane, ethyl acetate methanol respectively. FTIR characterization show the presence O-H, C-H C-O C=...

Kumis kucing (Orthosiphon stamineus) is a medicinal plant that can treat various diseases. has been known to contain bioactive compounds, namely polyphenol, alkaloid, and terpenoid which have antioxidant, antibacterial, antiviral, anti-inflammatory, anti-allergic anti-cancer activities. This study aims determine the phytochemical content, antioxidant activity, antibacterial activity of cat's wh...

Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potent...

Phytochemical investigation of a methanol extract Stixis scandens stems and leaves led to the isolation 3 nitrogen-containing compounds (1-3) 6 phenolics (4-9), which included 2 new glycosides, one phenolic amide glucoside, scandemide (1), other an indole alkaloid glycoside, stixilenin (2). Their structures were elucidated by spectroscopic (1D- 2D-NMR) spectrometric (HR-ESI-MS) analyses, acid h...

Three known compounds, stemofoline (1), (2'S)-hydroxystemofoline (2), and (11Z)-1',2'-didehydrostemofoline (3), along with two new alkaloids, stemaphylline (4) and stemaphylline-N-oxide (5), have been isolated from a root extract of Stemona aphylla. The structures of these alkaloids were determined on the basis of their spectroscopic data. The analysis of the crude dichloromethane extract by GC...

AIM OF THE STUDY The effects of pure alkaloid, mitragynine and a methanolic extract of kratom leaves were investigated on neuromuscular junction and compound nerve action potential. MATERIALS AND METHODS Wistar rats were killed by cervical dislocation and decapitated. The phrenic nerve-hemidiaphragms, hemidiaphragms and sciatic nerve were isolated. RESULTS Kratom methanolic extract present ...