the three components one pot synthesis of 2-amino-4h-benzo-[b] -pyran derivatives were obtained in good to excellent yields within short reaction time by condensing dimedone, aldehydes and malanonitrile or ethylcyanoacetate using a catalytic amount of (diacetoxyiodo)benzene as hypervalent iodine in aqueous ethanol under reflux conditions have been discussed. this aqua mediated knoevenagel-cyclo...

a facile and efficient method for the preparation of 1, 1-diacetates of aldehydes is improved.p2o5/sio2 catalyzed 1, 1-diacetates formation from aldehydes in dry media. advantages of this methodare the use of an inexpensive and selective catalyst with high yields in simple operation and shortreaction time under solvent-free conditions.

many aldehydes are important components of natural flavours. they are used in food, cosmetic, and biomedical industries in large amounts. plant cells or microorganisms carry out their production by biotransformation, which is one of the biotechnological methods that allow them to be defined as 'natural'. cell cultures of silybum marianum and peganum harmala have been studied with a vi...

aza heterocyclic compounds are major interest for organic chemists because of their mainly pharmacological activities and clinical applications such as antianxiety, antitumor, anticonvulsant, cardiotonic and vasorelaxant. this contribution describes an electrochemical approach for the preparation of nanosized particles of phthalazine in high yields and very short reaction time. the method is ba...

Chiral alcohols are ubiquitous in organic structures. One efficient method to generate chiral alcohols is the catalytic asymmetric addition of a carbon nucleophile to a carbonyl compound since this process produces a C-C bond and a chiral center simultaneously. In comparison with the carbon nucleophiles such as an organolithium or a Grignard reagent, an organozinc reagent possesses the advantag...