Stability studies play a critical role in assuring product quality at all points in the vaccine life cycle and havea major impact on the success of immunization programs worldwide. The purpose of stability study isdetermination of the vaccine quality under the variety of environmental factors and to establish a re-testperiod or a shelf life and recommended storage conditions. In this study thre...

Measles virus (MV) is a highly contagious agent which causes a major health problem in developing countries. We studied the effect of buthionine sulfoximine (BSO) on the replication of an AIK-HDC strain of MV and its induced apoptosis in Vero cell lines. Methods: In this study, toxicity of BSO on Vero cells was investigated first, resulted in determination of sub-lethal or non-toxic concentrati...

In early 1990, an outbreak of measles occurred in Kerman, (population 257, 284) Iran. Overall, 475 cases were identified and four died (case fatality ratio 5.4 per thousand). Illness was limited primarily to children below 15 years of age 166 (22.3%) were in children under five, 573 (77%) between 5-14 and six (0.8%) above 15 years of age. The age of the cases ranged from five months to 35 y...

k is a well-known fact that the uncertainties in measuring relative attenuation factors within a local or regional seismic network are usually high, due to noise of different kinds and unrealistic assumptions. Numerical experiments using nine synthetic seismograms, created using t* values ranging from 0.1 to 0.9 sec, reveal that the commonly used spectral ratio method is strongly affected by th...

stability studies play a critical role in assuring product quality at all points in the vaccine life cycle and havea major impact on the success of immunization programs worldwide. the purpose of stability study isdetermination of the vaccine quality under the variety of environmental factors and to establish a re-testperiod or a shelf life and recommended storage conditions. in this study thre...

Phosphorylation at a highly conserved serine residue (Ser-10) in the histone H3 tail is considered to be a crucial event for the onset of mitosis. This modification appears early in the G(2) phase within pericentromeric heterochromatin and spreads in an ordered fashion coincident with mitotic chromosome condensation. Mutation of Ser-10 is essential in Tetrahymena, since it results in abnormal c...

What is the relationship between plausibility logic and the principle of maximum entropy? When does the principle give unreasonable or wrong results? When is it appropriate to use the rule ‘expectation = average’? Can plausibility logic give the same answers as the principle, and better answers if those of the principle are unreasonable? To try to answer these questions, this study offers a num...

In 1991 Lorentzen and Nilsen showed how to use linear programming to prove lower bounds on the size of difference triangle sets. In this note we show how to improve these bounds by including additional valid linear inequalities in the LP formulation. We also give some new optimal difference triangle sets found by computer search. AMS Subject Classification: 05B10 Following Kløve [2] we define a...