BACKGROUND Prolactin (PRL) reduces joint inflammation, pannus formation, and bone destruction in rats with polyarticular adjuvant-induced arthritis (AIA). Here, we investigate the mechanism of PRL protection against bone loss in AIA and in monoarticular AIA (MAIA). METHODS Joint inflammation, trabecular bone loss, and osteoclastogenesis were evaluated in rats with AIA treated with PRL (via os...

Two experiments using soybean meal (SBM) or canola meal (CM) were conducted to investigate whether the choice of digestibility marker influenced the apparent ileal digestibility (AID) or standardized ileal digestibility (SID) of N and AA in diets supplemented with phytase. In each experiment, 18 barrows fitted with T-cannulas at the ileocecal junction were assigned to 3 diets consisting of a N-...

Context. Coordinated observations of a GOES B4.8 microflare with SDO’s Atmospheric Imaging Assembly (AIA) and the Ramaty High Energy Solar Spectroscopic Imager (RHESSI) on 2010 July 31 show that emission in all seven of AIA’s EUV channels brightened simultaneously nearly 6 min before RHESSI or GOES detected emission from plasma at temperatures around 10 MK. Aims. To help interpret these and AIA...

Background: Akathisia is a common adverse effect of antipsychotic drugs and is characterized by subjective feelings of restlessness. First-line treatment usually consists of propranolol, a beta adrenergic antagonist. However, propranolol does not seem to be efficacious in up to 70% of patients. This study was aimed to evaluate the effect of vitamin B6 versus propranolol on antipsychotic-induced...

DARPA’s Autonomic Information Assurance (AIA) program is exploring the use of automatic systems to detect and respond, at computer speeds, to high-speed computer security attacks. The first formal experiment of the AIA program, termed AIA Experiment 001, explored the relationship between the effectiveness of responses to scripted security attacks and the speed of those responses [5]. This paper...

Background: Intestinal inflammation, dysbiosis, intestinal permeability (IP) and bacterial translocation (BT) have been identified in patients with spondyloarthritis but the time at which they appear their contribution to pathogenesis of disease is still a matter debate. Objectives: To investigate time-course IP BT rat model reactive arthritis, subgroup SpA, adjuvant-induced arthritis model. Me...

Osteoarthritis (OA) is a common chronic inflammatory disease, characterized by cartilage degradation. The aberrant expression of matrix metalloproteinase-13 (MMP-13) plays a vital role in the pathogenesis of OA. The anti‑inflammatory property of docosahexenoic acid (DHA) was previously revealed and showed that DHA retards the progress of many types of inflammatory disease. To evaluate the proph...

OBJECTIVE This study examines the maternal characteristics and birth outcomes of infants of U.S. resident Asian-Indian-American (AIA) mothers and compares those to infants of U.S. resident Whites and African-American (AA) mothers. METHODS Single live births to U.S. resident mothers with race/ethnicity coded on birth certificate as AIA, non-Hispanic White, or non-Hispanic AA were drawn from NC...

AIM OF THE STUDY This study assessed the involvement of endogenous glucocorticoids (GCs) in the anti-arthritic properties of bee venom (BV) on antigen-induced arthritis (AIA) in rabbits. MATERIALS AND METHODS BV (1.5-6 microg/kg/day) was injected for 7 days before AIA induction, whereas the control group received sterile saline. The total and differential leukocyte count, PGE(2) levels in syn...

In recent years, automatic image annotation (AIA) has been applied to cross-media retrieval usually due to its advantage of mining correlations of images and annotation texts efficiently. However, some AIA methods just annotate images as a unit and the accuracy of annotation may not be acceptable. In this paper, we propose a kind of probabilistic model which may assign keywords to an un-annotat...