N-acylhomoserine lactone (AHL)-based quorum sensing (QS) is important for the regulation of proteobacterial virulence determinants. Thus, the inhibition of AHL synthases offers non-antibiotics-based therapeutic potentials against QS-mediated bacterial infections. In this work, functional AHL synthases of Pseudomonas aeruginosa LasI and RhlI were heterologously expressed in an AHL-negative Esche...

This paper mainly adopts descriptive analysis method and case study uses SERVQUAL model statistical to measure evaluate the service quality level of shuttle bus Al al-Bayt University. The concluded that order dimensions measuring was as follows: assurance, reliability, empathy at a medium level; then tangibility followed by responsiveness low for each. In general, students' satisfaction with se...

Ulva zoospores preferentially settle on N-acylhomoserine lactone (AHL) producing marine bacterial biofilms. To investigate whether AHL signal molecules also affect the success and rate of zoospore germination in addition to zoospore attraction, the epiphytic bacteria associated with mature Ulva linza were characterized and bacterial isolates representative of this community tested for the abili...

infection, even when challenged with comparatively low numbers of bacteria. The result is a triumph for the approach of mining bacterial metabolic diversity for applied uses. In this case, Dong et al. capitalized on the discovery that many bacteria can degrade, and so inactivate, AHLs. Earlier, the same group 5 had isolated hundreds of bacterial species from soil and screened them for the abili...

Praise be to God, Lord of the Worlds, and prayers peace upon Master Messengers, our Prophet Muhammad all his family companions. Then: There is no doubt that science hadith jurisprudence are among most important sciences in life a student knowledge, for first place: distinguish correct from bad, second understanding bad understanding, although there many hadiths inferred by fundamentalists juris...

Many bacteria determine their population density using quorum sensing. The most intensively studied mechanism of quorum sensing utilizes proteins of the LuxI family to synthesize a signaling molecule of the acylhomoserine lactone (AHL) type, and a protein of the LuxR family to bind AHL and regulate transcription. Genes regulated by quorum sensing often encode functions that are most effective w...

Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing (QS), links cell density to the expression of genes as diverse as those associated with virulence factors production of plant and animal pathogens, bioluminescence, antibiotic production, sporulation or biofilm formation. In Gram-negative b...