Until recently there was little understanding of the exact pathophysiology and treatment choices for stroke patients with Pseudobulbar affect (PBA). PBA is typically characterized by outbursts or uncontrollable laughing or crying and in the majority of patients, the outbursts being involuntary and incompatible with the patients' emotional state. PBA is a behavioral syndrome reported to be displ...

A diagnostic approach for neurodegeneration with brain iron accumulation: clinical features, genetics and brain imaging Uma orientação diagnóstica para neurodegeneração com acúmulo cerebral de ferro: aspectos clínicos, genéticos e de neuroimagem Rubens Paulo Araújo Salomão1, José Luiz Pedroso1, Maria Thereza Drumond Gama1, Lívia Almeida Dutra1, Ricardo Horta Maciel2, Clécio Godeiro-Junior3, Hsi...

Methods: Study subjects had a diagnosis of schizophrenia (DSM-IV-TR) with a duration of ≥2 years and had been clinically stable for ≥6 months but continued to have a Positive and Negative Syndrome Scale (PANSS) negative symptom score of ≥24 plus a score of ≥4 on at least 2 of the 4 core negative PANSS symptoms: blunted affect, passive social withdrawal, lack of spontaneity, and flow of conversa...

The message that assignment to placebo does not increase the risk of suicidal behaviour in patients who participate in double-blind randomized trials (Khan et al., 2001) is important but hardly surprising. The risk of suicidal behaviour is one of the exclusion criteria in placebocontrolled trials. Patients with this risk should be omitted from study samples. The analysis of Khan et al. (2001) s...

1970'li yıllarda genel kabul, yatırımcıların rasyonel davrandığı iken, yatırım kararlarının sadece bir yaklaşımla açıklanamayacağı gerçeği 1980'lerin başında gündeme gelmeye başlamıştır. Bu kapsamda yapılan çalışmalar, bireylerin konusunda karar verme süreçlerindeki iç ve dış faktörleri incelemeye yönelik olarak çeşitlenmiştir. Psikoloji, pazarlama, sosyoloji gibi sosyal bilimlerden beslenen ya...