Atrial fibrillation (AF) is one of the most common cardiac arrhythmias in the adult population. Propafenone is a class 1c antiarrhythmic agent that has an electrophysiologic profile suggesting that it might be potentially effective in recent-onset AF. The present study was undertaken, therefore, to examine the time course as well as the frequency of successful conversion in patients with recent...

Objective(s): Drug-induced atrial fibrillation (AF) is considered an adverse effect of chemotherapeutic drugs. AF is a crucial risk factor for stroke, heart failure, myocardial infarction, and mortality. Pulmonary veins (PVs) are considered triggers inducing AF, and the sinoatrial node (SAN) may modulate PV activity and participate in AF genesis. AF was associated with...

A prospective 1-year observational survey was designed to assess the management and control of atrial fibrillation (AF) in eight countries within the Asia-Pacific region. Patients (N = 2,604) with recently diagnosed AF or a history of AF ≤1 year were included. Clinicians chose the treatment strategy (rhythm or rate control) according to their standard practice and medical discretion. The primar...

Selecting appropriate treatment strategies for patients with persistent atrial fibrillation has often proved to be a quandary. Foregoing any debate on anticoagulant therapy, the remaining issue is whether the ultimate goal should be achieving and maintaining sinus rhythm or simply controlling the ventricular response during ongoing atrial fibrillation. Since atrial fibrillation affects 5% of th...

BACKGROUND There is a growing amount of evidence that inflammatory processes are involved in the development of atrial fibrillation (AF) and its complications. We decided to investigate the behavior of osteoprotegerin (OPG) and TNF-related apoptosis inducing ligand (TRAIL) in terms of acute onset of AF. METHODS AND RESULTS We included 60 patients with acute onset of AF, candidates for pharmac...

Atrial fibrillation (AF) is the most common type of arrhythmia and has a large global burden. In general, treatment of AF is based on medication and consists of rate and rhythm control together with anticoagulation. However, surgical treatment may be required in patients with AF combined with organic valvular heart diseases or who experience recurrence despite medication. In addition, surgical ...

Introduction Percutaneous catheter ablation is an established rhythm control strategy for the treatment of atrial fibrillation (AF). Recent clinical trials show that catheter ablation of atrial fibrillation reduces the risk of recurrence of symptomatic AF, atrial flutter, or atrial tachycardia, and may also reduce subsequent hospitalizations and improve quality of life compared to antiarrhythmi...

INTRODUCTION AND OBJECTIVES Atrial remodeling is responsible for the early recurrence of atrial fibrillation (AF) after cardioversion. Recently, it has been shown that the C-reactive protein (CRP) level is elevated in patients with AF, indicating that inflammation may play a role in the pathogenesis of this arrhythmia. We postulated that a high CRP level would predict early recurrence of AF aft...

Atrial fibrillation (AF) is characterized by rapid, seemingly chaotic atrial activation, characterized by the lack of an organized P wave and irregularly irregular ventricular activation (QRSs) on surface ECG. AF manifests as a result of multiple heterogeneous groups of disorders. For example, AF can occur idiopathically (so-called lone AF), be related to familial inheritance with specific gene...