Saposin-like proteins (SAPLIPs) from soil-transmitted helminths play pivotal roles in host-pathogen interactions and have a high potential as targets for vaccination against parasitic diseases. We have identified two non-orthologous SAPLIPs from human and dog hookworm, Na-SLP-1 and Ac-SLP-1, and solved their three-dimensional crystal structures. Both proteins share the property of membrane bind...

The adsorption properties of new ceramics titania (titanium dioxide, Ti02) as a column packing material for high performance liquid chromatography (HPLC) were investigated in our recent studies. The adsorption mechanism of titania was found to be different from that of silica gel; the titania adsorbs acidic compounds rather than basic compounds, while silica gel adsorbs basic compounds. In addi...

Aminopropyl-functionalized SBA-15 mesoporous silica was used as a support to adsorb myoglobin. Then, in order to avoid the leakage of adsorbed myoglobin, lysozyme was covalently tethered to the internal and external surface of the mesoporous silica with glutaraldehyde as the coupling agent. The property of amino-functionalized mesoporous silica was characterized by N(2) adsorption-desorption an...

Antimicrobial peptides, bacteriocins, produced by lactic acid bacteria were adsorbed on the cells of producing strains and other gram-positive bacteria. pH was a crucial factor in determining the degree of adsorption of these peptides onto cell surfaces. In general, between 93 and 100% of the bacteriocin molecules were adsorbed at pHs near 6.0, and the lowest (< or = 5%) adsorption took place a...

The purpose of the investigation is to analyze the pros and cons of existing sorption models, as well as experimental methods. In addition, it summarizes existing sorption data in order to understand the phenomenon of VOC sorption on building materials better and to direct future research. We found that existing sorption models can be generally classified into either first order adsorption/deso...

Silica (SiO2)-derived nanoadsorbents are a powerful and attractive tool for the extraction and separation of rare earth elements (REE) from many perspectives such as reusability, efficiency and minimum impact on the environment. In the present work, we investigated two different methods of adsorption down to the molecular level: (1) the mechanism of the coordination of different groups of REE (...

A fundamental study about the selective foam separation of protein mixture was carried out. A solution containing two proteins, Ovalbumin (OA) and Lysozyme (LZ), and an anionic surfactant, Sodium Dodecyle Sulfate (SDS), was adjusted to pH 6.0 which refered to an intermediate state between the isoelectric points of the proteins. The solution was processed by continuous foam separation. The resul...

Interaction of biomaterials with blood components including neutrophils is responsible for some of the clinical complications that have occurred in cardiopulmonary bypass, hemodialysis, and ventricular assist procedures. The possibility of inhibiting the initial adhesion of neutrophils to biomaterials has been studied extensively, but the problem remains unsolved. In this study, we investigated...

Interaction of biomaterials with blood components including neutrophils is responsible for some of the clinical complications that have occurred in cardiopulmonary bypass, hemodialysis, and ventricular assist procedures. The possibility of inhibiting the initial adhesion of neutrophils to biomaterials has been studied extensively, but the problem remains unsolved. In this study, we investigated...

To explore the possibility of using graphene based biosensor, adsorption of hydrogen peroxide on graphene has been investigated using density functional theory. The electronic properties of defect free and defective graphene in the presence of different number of hydrogen peroxide have been studied. The graphene with the most stable configuration defect named as SW defect is considered. The hig...