The aim of this article is to highlight the importance of Eccrine Spiradenoma (ES) in the differential diagnosis of chronic soft tissue lesions of the foot. These include a broad spectrum of nonneoplasm lesions, as well as benign and malignant neoplasms. Benign tumours include deep fibromatosis, neurogenic tumours, lipoma, haemangioma, synovial proliferations, and exceptionally rare on foot, sk...

Complex adnexal masses are common and often present as a diagnostic dilemma. Many of these complex adnexal masses require timely recognition and treatment. Therefore, it is important to have a good differential diagnostic approach to these lesions. The classic differential for complex adnexal mass is the mnemonic "CHEETAH." This mnemonic may be a helpful memory device for residents, especially ...

Maternal adnexal torsion in pregnancy, with a reported incidence of 1-10 per 10,000 spontaneous pregnancies, is very uncommon. Since it has been described as a severe complication after controlled ovarian hyper-stimulation for in vitro fertilization (IVF), it is more common in IVF pregnancies. This condition mainly occurs in the first trimester; it is rare during the late second trimester. Cons...

In this article, we provide an update on incidence rates of ophthalmic non-Hodgkin's lymphoma (NHL), in the context of other NHL, in the USA. We also provide population-based estimates of incidence and survival for ocular adnexal NHL, the most common form of ophthalmic NHL, for which descriptive patterns have not been previously reported. Ophthalmic and ocular adnexal NHL have unique incidence ...

AIMS To report the clinicopathological characteristics of patients with ocular adnexal marginal zone B cell lymphoma (MZBL) with IgG4-positive plasma cells. METHODS 114 biopsy samples of ocular adnexal MZBLs were analysed. MZBLs with IgG4-positive plasma cells were included when the IgG4:IgG ratio was >40% (IgG4-related group). The serum levels of each subclass of immunoglobulins and soluble ...

background and objectives: the diagnosis of pregnancy associated adnexal masses is rising due to routine utilization of sonography in prenatal care. the purpose of this study was to describe pregnancy associated adnexal masses over a period of 10 years. patients and methods: a retrospective study was reviewed hospital records of all pregnant women with adnexal mass that underwent surgical resec...

despite of the fact that the vulva contains a high density of apocrine and anogenital mammary glands in addition to eccrine glands and folliculosebaceous units, the benign vulvar adnexal tumours are rare. though the varied clinical presentation and diverse histopathological spectrum of vulvar neoplasms has amazed the pathologists, only few studies have been reported in literature. the present f...

Historically it has been shown repeatedly that single high doses of radiation do not allow a therapeutic differential between tumor and critical normal tissues but dose fractionation does. The purpose of conventional dose fractionation is to increase dose to the tumor while preserving normal tissue function. Tumors are generally irradiated with 2Gy dose per fraction delivered daily to a more or...

Laparoscopic supracervical hysterectomy (LSH) is an example of a partial hysterectomy, performed due to benign gynaecological complaints. Better endoscopic instruments and operational techniques have led to a great reduction in the number of abdominal hysterectomies. It is believed that LSH is a safe and minimally invasive hysterectomy technique. The Cochrane Database meta-analysis proves the b...

Cutaneous cylindroma is an adnexal tumour with apocrine differentiation. A predisposition to multiple cylindromas is seen in patients with Brooke-Spiegler syndrome, who carry germline mutations in the tumour suppressor gene CYLD. Previous studies of inherited cylindromas have highlighted the frequent presence of bi-allelic truncating CYLD mutations as a recurrent driver mutation. We have previo...