نتایج جستجو برای: admixture elements

تعداد نتایج: 281614  

Journal: :Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2005
David Reich Nick Patterson

Admixture mapping is the first experimentally practical method for carrying out a whole-genome association scan, and is thus a promising method for detecting risk factors for common disease. The goal of the community should now be to aggressively test whether the method is useful in practice for localizing disease genes, by carrying out at least three high-powered studies. We also propose a str...

2011
Maria A. Tonione Natalie Reeder Craig C. Moritz

Invasive species often have reduced genetic diversity, but the opposite can be true if there have been multiple introductions and genetic admixture. Reduced diversity is most likely soon after establishment, in remote locations, when there is lower propagule pressure and with stepping-stone colonizations. The common house gecko (Hemidactylus frenatus) was introduced to Moorea, French Polynesia ...

1997
M. B. Voloshin

Bound on V + A admixture in the b → c current from inclusive vs. exclusive semileptonic decays of B mesons. Abstract An admixture of a right-handed b → c current in the semileptonic weak decays of the B mesons would give a significantly different contribution to the inclusive rate of the decays B → l ν X c as compared to the exclusive decay B → D * l ν at zero recoil. Thus a difference in the v...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2006
Matthew L Freedman Christopher A Haiman Nick Patterson Gavin J McDonald Arti Tandon Alicja Waliszewska Kathryn Penney Robert G Steen Kristin Ardlie Esther M John Ingrid Oakley-Girvan Alice S Whittemore Kathleen A Cooney Sue A Ingles David Altshuler Brian E Henderson David Reich

A whole-genome admixture scan in 1,597 African Americans identified a 3.8 Mb interval on chromosome 8q24 as significantly associated with susceptibility to prostate cancer [logarithm of odds (LOD) = 7.1]. The increased risk because of inheriting African ancestry is greater in men diagnosed before 72 years of age (P < 0.00032) and may contribute to the epidemiological observation that the higher...

Journal: :Molecular biology and evolution 2009
Eric Durand Flora Jay Oscar E Gaggiotti Olivier François

Genetic admixture of distinct gene pools is the consequence of complex spatiotemporal processes that could have involved massive migration and local mating during the history of a species. However, current methods for estimating individual admixture proportions lack the incorporation of such a piece of information. Here, we extend Bayesian clustering algorithms by including global trend surface...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور مرکز - دانشکده زبانهای خارجی 1391

the primary goal of the current project was to examine the effect of three different treatments, namely, models with explicit instruction, models with implicit instruction, and models alone on differences between the three groups of subjects in the use of the elements of argument structures in terms of toulmins (2003) model (i.e., claim, data, counterargument claim, counterargument data, rebutt...

Journal: :Current opinion in genetics & development 2016
Jeffrey D Wall Debora Yoshihara Caldeira Brandt

Modern humans evolved in Southern or Eastern Africa, and spread from there across the rest of the world. As they expanded across Africa and Eurasia, they encountered other hominin groups. The extent to which modern and 'archaic' human groups interbred is an area of active research, and while we know that modern humans interbred with Neanderthals and Denisovans, there is not yet agreement on how...

Journal: :Blood 2011
Maria Clara F da Silva Luciana W Zuccherato Flavia C Lucena Giordano B Soares-Souza Zilma M Vieira Sérgio D J Pena Marina L Martins Eduardo Tarazona-Santos

This study was developed after approval by the Ethical Committees from the Universidade Federal de Minas Gerais and the Hemominas Foundation. We estimated admixture in unrelated subjects with sickle cell disease (SCD, n = 200) and healthy blood donors (n = 291), sampled across different regions of the state of Minas Gerais (Figure S1), a geographic area in South Eastern Brazil similar to that o...

Journal: :Annals of human genetics 2006
V M Zembrzuski S M Callegari-Jacques M H Hutz

Ten ancestry informative markers were investigated in 101 coronary artery disease patients and 102 healthy controls from a Southern Brazilian population, in order to determine if stratification occurs in this population. The degree of African admixture detected in this population was estimated to be as high as 6%, but no differences between cases and controls were observed. Using an African Anc...

2013
D. Sreehari Rao I.V.Ramana Reddy

Admixtures and the water have an important role on application of concrete. The study is aimed at investigating the effect of strong acids as mixing water on setting times, soundness and compressive strength of admixture cements. This paper therefore presents the result and findings of an experimental research on the influence of strong acids on setting and strength development of admixture cem...

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