H EMATOPOIESIS IS A complex process in which pluripo-tent stem cells proliferate and differentiate to generate the full complement of mature blood cells. More than 30 hemopoietic cytokines and growth factors that increase or decrease progenitor proliferation and differentiation have been cloned and characterized. 1-3 Although the biological effects of these cytokines and growth factors on stem ...

In the food industry, microbial adhesion to equipment surfaces and subsequent development of biofilm are very serious issues because of potential to cause cross-contamination, which leads to lowered shelf-life, food spoilage, and transmission of disease [1-4]. Adhesion and subsequent growth on surfaces is a common strategy of bacteria for survival in both natural habitats and man-made environme...

PURPOSE To investigate the association between soluble apoptosis and adhesion molecules and the development of proliferative vitreoretinopathy (PVR) after reattachment surgery for rhegmatogenous retinal detachment (RRD). METHODS A multiplex immunoassay was used to measure soluble Fas (sFas), sFas ligand (sFasL), soluble intercellular adhesion molecule (sICAM)-1, and soluble vascular cell adhe...

Successful human reproduction remains an enigma, but this is slowly changing in the current era of expanding scientific knowledge. The discovery of various molecular factors such as adhesion molecules, proteases and cytokines have in recent years been at the forefront of medical research. The growing importance of immunology in particular has led to novel new immuno-modulatory therapies and inc...

Leukocyte recruitment to sites of inflammation, infection or vascular injury is a complex event that is orchestrated by a tightly coordinated sequence of interactions between leukocytes and cells of the vessel wall, especially endothelial cells. These interactions are controlled by the expression and activation of various adhesion receptors and protease systems. This review will focus on novel ...

Objective(s): The present study investigated the prevalence of genes encoding for exotoxins, adhesion and biofilm factors in Staphylococcus aureus isolates obtained from samples in a referral burn hospital in Tehran, Iran.Materials and Methods: S. aureus isolates obtained from patients, personnel and surfaces in the wards of a burn hospi...

When a sperm and an oocyte unite upon fertilization, their cell membranes adhere and fuse, but little is known about the factors regulating sperm-oocyte adhesion. Here we explored the role of β-catenin in sperm-oocyte adhesion. Biochemical analysis revealed that E-cadherin and β-catenin formed a complex in oocytes and also in sperm. Sperm-oocyte adhesion was impaired when β-catenin-deficient oo...

Candida albicans and Candida dubliniensis are two pathogenic yeasts particularly hazardous to immunocompromised patients. Adhesion of yeast cells to epithelium is considered one of the virulence factors and its study is of major importance. The main aim of this study was the comparison of the influence of physico-chemical properties on the adhesion of C. albicans and C. dubliniensis to epitheli...

The process of angiogenesis plays an important role in many physiological and pathological conditions. Inhibition of endothelial cell (EC) apoptosis providing EC survival is thought to be an essential mechanism during angiogenesis. Many of the angiogenic growth factors inhibit EC apoptosis. In addition, the adhesion of ECs to the extracellular matrix or intercellular adhesion promotes EC surviv...

Crop yield loss as a result of disease has an economic impact on many people. To protect against disease, plant pathologists have developed various fungicides and disease resistant cultivars. In parallel, pathogens have evolved to escape from disease protection measures through, for example, the emergence of fungicide resistant isolates and the breakdown of disease resistant cultivars. To resol...