BACKGROUND & AIMS Specific mutations in the adenomatous polyposis coli (APC) gene can lead to an attenuated form of familial adenomatous polyposis (AFAP). Although AFAP mutation carriers have a 69% risk of colorectal cancer by age 80, clinical recognition remains a challenge in some cases because they present with few colonic adenomas and are difficult to distinguish clinically from patients wi...

PURPOSE OF REVIEW Gastrointestinal polyps are commonly encountered during childhood and are one of the most common causes of rectal bleeding in this age group. Most polyps are benign and located in the colon, with the most frequent type being juvenile polyps. However, in older pediatric patients, if multiple polyps are present, in patients who have a positive family history, or if polyps are lo...

Six patients from one family and one solitary patient with juvenile polyposis coli are described. The histological changes in colonic polyps formed a spectrum from juvenile polyps, through focal to extensive adenomatous change, to adenocarcinomas. One patient aged 49 years had an adenocarcinoma of the colon and in another, aged 33, with rectal polyps and metastatic cancer this was suspected alt...

Background. Although the size of colon polyps is an important risk factor for colorectal cancer, a standardized measurement technique has yet to be determined. In clinical practice, most endoscopists estimate polyp size by uncertain visual estimation; however, colonoscopic polypectomy is indicated for adenomatous polyps more than 5 mm in diameter. We have therefore developed a novel calibrated ...

Colorectal polyp may be defined as growth of tissue on the lining of colon and rectum. It is assumed that adenomatous polyp is the most potent precursor of colorectal cancer [1]. Consequently colonoscopic polypectomy can reduce risk of colorectal cancer [2]. All polyps are not cancerous nonetheless large number of colon cancers grow as a consequence of adenomatous polyp [3]. Though colorectal c...

A case is reported here of juvenile polyposis in a 15year-old girl. She was diagnosed upon the assessment of the dysenteric syndrome. Coloscopy and gastroscopy had shown polyps of variable size whose histological study confirmed the hamartomatous character typical of the youthful non adenomatous polyps free of dysplasia. There was no localization in the small bowel. Coloprotectomy with ileoanal...

Abstract The narrow-band imaging (NBI) International Colorectal Endoscopic (NICE) classification is based on pictures of colon polyps viewed through a spectrum. categorisation utilises staining, surface structure, and vascular patterns to differentiate between hyperplastic adenomatous polyps. It known that accuracy the NICE for colorectal varies depending localisation in colon.The aim this stud...

Background: Familial adenomatous polyposis (FAP) is an autosomal dominant disorder caused by a mutation in the coli (APC) gene. FAP characterized development of multiple polyps (>100) colon. The aim this study was to evaluate prevalence gastroduodenal patients referred Taleghani hospital, teaching referral center Tehran, Iran. Materials and Methods: Front-view side-view endoscopies were perf...

AIMS To study the expression of HLA-DR antigen in the different histological types of gastric polyps. METHODS Ninety five cases of gastric polyps were histologically classified and examined for the presence of Helicobacter pylori, and for degree and type of inflammation. Further sections were stained immunohistochemically for HLA-DR antigen expression in the epithelium using a monoclonal anti...

Colorectal polyps are an important albeit uncommon cause of rectal bleeding in children. Colonoscopy promotes both rapid and accurate diagnosis and the opportunity for immediate therapeutic polypectomy. A 10 year audit of polyps diagnosed and treated endoscopically has been undertaken in the children's endoscopy unit. Twenty nine polyps were diagnosed from 730 colonoscopies; 24 were juvenile, t...