Bile acids are potential carcinogens in gastrointestinal cancer, and interact with nuclear and membrane receptors to initiate downstream signaling. The effect of TGR5 [also known as G protein-coupled bile acid receptor 1 (GPBAR1)] on cancer progression is dependent on the tissue where it is activated. In this report, the function of TGR5 expression in cancer was studied using a bioinformatic ap...

We herein present the first case to be reported of synchronous quadruple primary cancer of the thyroid, breast, pancreas and stomach in a 70-year-old female. Fluorine-18-fluorodeoxyglucose (FDG)-positron-emission tomography/computed tomography (PET/CT) revealed increased FDG activity in the thyroid, left breast, pancreatic body and antrum of the stomach. To make a definitive diagnosis of synchr...

In the present study, we fabricated tungsten trioxide nanoparticles (WO3 NPs) from a complex [W(C13H10NO)3] of ligand N-salicylideneaniline with tungstic acid as precursor. Nanoparticles were synthesized using direct thermal decomposition method. These evaluated for cytotoxicity influence on human breast cancer MCF7 cell line (adenocarcinoma). The observed results suggested that WO3 can destroy...

PURPOSE Carcinogenesis is an adaptive process between nascent tumor cells and their microenvironment, including the modification of inflammatory responses from antitumorigenic to protumorigenic. Radiation exposure can stimulate inflammatory responses that inhibit or promote carcinogenesis. The purpose of this study is to determine the impact of radiation exposure on lung cancer progression in v...

The patient is a 56-year-old Japanese woman who suffered from breast cancer and ovarian cancer at intervals of 6 years, and was also complicated by two episodes of dermatomyositis, each of which occurred simultaneously with each of two cancers. When she was 51 years old, she developed dermatomyositis for the first time 6 months after the resection of breast cancer, whose histological type was t...

Breast cancer refers to several types of neoplasm arising from breast tissue, the most common being adenocarcinoma of the cells lining the terminal duct lobular unit. Breast cancer is the most prevalent cancer in women all around the globe, and is the second leading cause of cancer deaths in women. However, the prognosis is good if detected early. The overall 5-year relative survival is 88% in ...

background: breast cancer is third order malignancy in women among other malignancies.   various studies showed that incidence of breast cancer can be lower down by early detection of breast cancer. mammographic screening is considered more effective modality in detecting early stage breast cancer in women who are at elevated risk for breast cancer. the aim of this study is to report the result...

Medicinal plants have been investigated for possible anti-cancer effects. The aim of the present study was to examine the cytotoxic activity of several medicinal plants on different tumor cell lines. 11 selected plant species which have been used in folkloric prescriptions were collected from different sites of Hamedan district of Iran. The methanolic extracts of the plants were prepared and th...

Purpose: Carcinogenesis is an adaptive process between nascent tumor cells and their microenvironment, including the modification of inflammatory responses from antitumorigenic to protumorigenic. Radiation exposure can stimulate inflammatory responses that inhibit or promote carcinogenesis. The purpose of this study is to determine the impact of radiation exposure on lung cancer progression in ...

Abstract Aims Mucinous adenocarcinoma of the breast is rarely encountered clinically, and makes up only 0.01% Breast cancer (BC) cases < 1% male (MBC). We describe an extremely rare case mucinous carcinoma in accessory axillary tissue a male. Case details A 48-year old presented with subcutaneous lump his left axilla. Ultrasound described 30mm hypoechoic mass core biopsy confirmed adenoc...