The effect of exposure of male mice to a horizontal running wheel (Fast-TracTM) on conditioned place preference (CPP) and hyperlocomotion induced by methamphetamine (METH) was determined. In the first experiment eleven-week-old male ICR mice were divided into three groups and exposed to three different environments (housed individually with (group A) or without a running wheel (group B), or hou...

This paper deals with the design of aluminum alloy wheel for automobile application which is carried out paying special reference to optimization of the mass of the wheel. The Finite Element analysis it shows that the optimized mass of the wheel rim could be reduced to around 50% as compared to the existing solid disc type Al alloy wheel. The FE analysis shows that the stress generated in the o...

Open-loop position estimation methods are commonly used in mobile robot applications. Their strength lies in the speed and simplicity with which an estimated position is determined. However, these methods can lead to inaccurate or unreliable estimates. Two position estimation methods are developed in this paper, one using a single optical flow sensor and a second using two optical sensors. The ...

We investigated in detail the dermoscopic and histopathological findings in a case of a superficial type of multiple basal cell carcinomas (BCCs). These multiple lesions (occurring in the chest, neck, and back) showed three different findings, respectively. Dermoscopy of the erythematous and brown-colored patch on the anterior chest showed spoke wheel areas, and the histopathological cross-sect...

In road vehicles, wheel locking can be prevented by means of closedloop Anti-lock Braking Systems (ABS). Two output measured variables are usually considered for regulation: wheeldeceleration and wheel longitudinal slip. The traditional controlled variable used in ABS is the wheel deceleration, since it can be easily measured with a simple wheel encoder; however, it can be dynamically critical ...

Predicting the tractive limitations of locomotion gears is of critical importance in a robotic vehicle system on natural terrain. In particular, it is imperative for an unmanned mobile robot to avoid getting stuck in loose soil to retain its mobility. From this perspective, this paper attempts to theoretically predict the limitations of a typical wheel in such loose soil based on traditional so...

In this paper the potential of predictive control in a hybrid wheel loader is estimated using related research results as a basis. The application of hybrid technology to a wheel loader application is discussed and differences between on-road vehicles and wheel loaders are clarified. The main part of the related research has its focus on on-road vehicles where the usage patterns are more cohere...

One of the mechanisms through which regular exercise contributes to weight maintenance could be by reducing intake and preference for high-fat (HF) diets. Indeed, we previously demonstrated that wheel-running rats robustly reduced HF diet intake and preference. The reduced HF diet preference by wheel running can be so profound that the rats consumed only the chow diet and completely avoided the...

BACKGROUND Chronic fatigue stress (CFS) is an important health problem with unknown causes and unsatisfactory prevention strategies, often characterized by long-lasting and debilitating fatigue, myalgia, impairment of neuro-cognitive functions along with other common symptoms. The present study has been designed to explore the protective effect of statins against running wheel activity induced ...

Voluntary wheel running can potentially be used to exacerbate the disease phenotype in dystrophin-deficient mdx mice. While it has been established that voluntary wheel running is highly variable between individuals, the key parameters of wheel running that impact the most on muscle pathology have not been examined in detail. We conducted a 2-week test of voluntary wheel running by mdx mice and...