Objective: Early and sufficient nutritional support is vital to improve outcomes in patients with traumatic brain injury. This study aims to determine the effects of dietitian involvement in the nutritional and clinical outcomes in patients with traumatic brain injuries admitted to the neurosurgical ICU. Materials & Methods: Forty eight male patients with traumatic brain injuries admitted to P...

conclusions the findings of this study indicated that the economic burden of tbis was high in fatal accidents in fars province so that it was equivalent to 0.00011% of iran’s gross domestic product (gdp) in 2013. therefore, more attention has to be paid to the rules to prevent the fatal accidents. results deaths resulting from tbis due to traffic accidents in shiraz imposed 6.2 billion rials (5...

a motor vehicle seat belt use law for the driver and front-seat passenger was implemented in taiwan on june 1, 2001. the purpose of this study was to determine the effect of motor vehicle seat belt use on the severity of traumatic brain injuries because of motor vehicle accidents.data were collected from 27 major teaching hospitals four years before june 1, 2001 and until may 31, 2013. a total ...

Traumatic brain injury is considered as one of the main causes of morbidity and mortality worldwide. Apart from primary mechanical injury, Secondary injuries due to inflammation and apoptosis result in great neuronal damage. Current treatments are not able to regenerate the damaged part and prevent future sequels. Using human stem cells with self-assembling scaffolds may be promising in treatme...

although the majority of the patients with traumatic brain injury presents with injuries involving the extremities, there was a clear paucity of adequate experimental polytrauma models. to close this gap, we conducted several studies to establish two different polytrauma mice models including both closed and open traumatic brain injury. male c57bl mices with a mean weight of 23g were anesthetiz...

OBJECTIVE The aim of this study is to map and evaluate the available resources and the premises of traumatic head injury management in the Nordic countries, before the implementation of a Nordic adaption of the Brain Trauma Foundation guidelines for prehospital management. METHODS The study is a synthesis of two cross-sectional surveys. Questionnaires were used to collect data on the annual n...

The bcl-2 and caspase families are important regulators of programmed cell death in experimental models of ischemic, excitotoxic, and traumatic brain injury. The Bcl-2 family members Bcl-2 and Bcl-xL suppress programmed cell death, whereas Bax promotes programmed cell death. Activated caspase-1 (interleukin-1beta converting enzyme) and caspase-3 (Yama/Apopain/Cpp32) cleave proteins that are imp...

Background: The association of delirium with poor outcomes creates a complex picture in traumatic brain injury patients by exacerbating an already increased risk for neurobehavioral sequelae. Haloperidol is commonly used for agitation and delirium; however, adverse events are concerns associated with its use in traumatic brain injury patients. The objective of this study was to assess the safet...

PURPOSE OF REVIEW This review discusses recent studies that have implications for potential neuropharmacological interventions which target cognitive deficits resulting from traumatic brain injury or stroke. RECENT FINDINGS An important new study concerning the activity of N-methyl-D-aspartate (NMDA) receptors after brain injury reveals that previous influential hypotheses about an increase i...