It is widely accepted that improved perfusion of viable myocardium preserves cardiac function and conveys longterm survival benefits after myocardial infarction (MI). Mechanical reperfusion for acute MI targets optimal revascularization of the epicardial artery but also aims at improved myocardial salvage. Intracoronary thrombus (especially large amounts) makes both of these goals difficult to ...

Myocardial ischemia (MI) resulting in infarction is an important cause of mortality and morbidity worldwide. Acute ischaemia rapidly impairs myocardial contractile function. Myocardial dysfunction persisting for several hours after transient non-lethal ischaemia, eventually resulting in full functional recovery is termed as myocardial stunning. Hibernation is now thought to be the consequence o...

Abstract Background According to 4th Universal Definition of Myocardial Infarction (MI), it is possible differentiate clinically type 2 MI (T2MI) from 1 (T1MI) and acute myocardial injury (AMI). However, in many cases this differentiation may be difficult. To date there are poor data that allow distinguish AMI, T2MI T1MI the changes absolute or relative values biomarkers necrosis. We sought com...

  Background :Impact of substance abuse on outcome of hospitalized patients with acute myocardial infarction (MI) is a frequent question. Available studies show disagreements over its impact, thus we performed this study to find a clear answer.   Methods : In a cross sectional study, 304 patients (include 152 consecutive opium dependents and equal number of independents) with acute MI admitted ...

Ischemic heart disease (IHD) is the leading cause of death and disability worldwide. For patients presenting with an acute ST-segment elevation myocardial infarction (STEMI) the treatment of choice is timely reperfusion by primary percutaneous coronary intervention (PPCI). However, the process of reperfusion can in itself independently induce myocardial injury and cardiomyocyte death—a phenomen...

Background: Autopsy changes in sudden cardiac death due to Acute Myocardial Infarction (MI), is a real challengefor Forensic Pathologist. Immuno-histochemistry has proved significant role identifying myocardial necrosis.Aim: To find the incidence of deaths ischemia, its among postmortem cases and therole C9 infarction by immuno-histochemical staining methods amongautopsy cases.Materials Methods...

The term, acute coronary syndrome (ACS), describes a spectrum of clinical conditions ranging from ST-segment elevation myocardial infarction (STEMI) to non–ST-segment elevation MI (N–STEMI) and unstable angina (UA) (Fig. 119.1) (1). These manifestations of acute myocardial ischemia may revert to the presymptomatic state or evolve into a non-Q wave (also termed nontransmural) MI or to Q wave (or...

Regional distribution of pulmonary blood flow and ventilation was determined with the 133xenon technic in the erect position at the bedside in 15 patients an average of 6 days after uncomplicated myocardial infarction (MI) and in five patients with severe angina in the same coronary care unit. Follow-up studies were repeated within 3 to 25 weeks on six of the patients with MI. There was marked ...

More than 1.2 million patients suffer from new or recurrent ischemic events occur annually. This includes an estimated 565,000 cases of first and 300,000 cases of recurrent myocardial infarction (MI). Although mortality from acute MI has declined in recent years, it still remains high at 25% to 30%. Despite its high mortality, prognosis can be improved with timely and effective use of evidence-...