mental stress and daily crises comprise a part of physical and mental threats. perceived stress is a physical and mental threat, as well. perceived stress is a psychological process during which the individual considers his/ her physical and psychological welfare as being threatened. since idiopathic thrombocytopenic purpura (itp) is one of the chronic diseases being able to affect patients' pe...

immune thrombocytopenic  purpura (itp) is an autoimmune bleeding disorder characterized by production  of auto-antibodies against platelet antigens. it is obvious that regulatory t cells (tregs) have a major role in controlling immune homeostasis and preventing autoimmunity. to investigate the frequency and functions of tregs, twenty itp patients and twenty age- and sex- matched healthy control...

CCUMULATION of lipid, presumably phospholipid, in histiocytes of the splenic cords has been seen in association with thrombocytopenic purpura in six patients operated on in Barnes Hospital. At the time that each of the first four were examined, a diagnosis or description of lipid histiocytosis of the spleen was made, but after that the constant association with thrombocytopenic purpura was note...

Idiopathic thrombocytopenic purpura (ITP) is characterized by a low platelet count, which is the result of both increased platelet destruction and insufficient platelet production. Although the development of autoantibodies against platelet glycoproteins remains central in the pathophysiology of ITP, several abnormalities involving the cellular mechanisms of immune modulation have been identifi...

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease defined by a low platelet count secondary to accelerated platelet destruction by anti-platelet antibodies. The resulting bleeding diathesis can present a therapeutic dilemma. We have treated two cases of ITP in which ureteral stones were successfully extracted by transurethral ureterolithotripsy (TUL) and extracorporeal shock wa...

Recent reports have suggested an association between Helicobacter pylori infection and idiopathic thrombocytopenic purpura (ITP). The prevalence of H pylori infection and the effect of its eradication in a series of 30 ITP patients were investigated. H pylori infection has been documented in 13 patients (43.33%) by 13C urea breath test and confirmed by histologic examination. Bacterium eradicat...

Platelets are anuclear blood cells whose function is to form blood clots when we injure ourselves, to prevent excessive blood loss. Thrombocytopenia is a relative low number of platelets in the blood. Thrombocytopenia has several possible causes, including the trapping of platelets in spleen, reduced production of platelets and increased breakdown of platelets. Some examples of an increase in p...

Hematologic abnormali"es are generally present among systemic lupus erythematosus pa"ents. Idiopathic thrombocytopenic purpura can be the first manifesta"on of SLE, followed by other symptoms and signs of disease appearing several years later. Although bleeding due to immune thrombocytopenic purpura is usually mild and occurs in mucocutaneous surfaces, but it may be severe and represent in u...

Background: Bernard-Soulier syndrome (BSS) is a rare, autosomal recessive platelet function disorder which is commonly mistaken for idiopathic thrombocytopenic purpura (ITP).The report includes seven cases of BSS that have been diagnosed and treated as ITP for a long time. Methods: Between 2006 and 2016, data of seven BSS patients who have long been diagnosed and treated as ITP were collected ...