cyclizine (1-benzhydryl-4-methyl-piperazine, cas 82-92-8, cyc, i), a piperazine derivative, belongs to h1 antihistamine group of drugs that shows such pharmacological properties as anti-inflammatory, anti-allergic and anti-platelet effects, similar to other h1-receptor antagonists. in this study, two new tolyl and cumene derivatives of i (1-ethyl-4-[(p-isopropylphenyl) (p-tolyl) methyl]-piperaz...

Introduction Determining the area-at-risk (AAR) in acute coronary syndromes (ACS) after Percutaneous Coronary Intervention (PCI) is remaining a challenge and is crucial to estimate the myocardial salvage and especially the AAR/infarct-size ratio. Depicting the AAR accurately maximizes then ability to test acute imaging paradigms. In addition, evaluating the occurrence of early hemorrhagic trans...

Therapists certified in lymphedema management are skilled and prepared to address male genital edema mainly through manual lymphatic drainage and compression bandaging. That being said, there remains a need to further develop and establish treatment protocols in this area of edema management, especially in inpatient, acute care hospital settings. Many individuals who are hospitalized for variou...

Myocardial interstitial edema forms as a result of several disease states and clinical interventions. Acute myocardial interstitial edema is associated with compromised systolic and diastolic cardiac function and increased stiffness of the left ventricular chamber. Formation of chronic myocardial interstitial edema results in deposition of interstitial collagen, which causes interstitial fibros...

Dengue hemorrhagic fever (DHF) is a severe febrile disease, characterized by abnormalities in hemostasis and increased vascular permeability, which in some cases results in hypovolemic shock syndrome and in dengue shock syndrome. The clinical features of DHF include plasma leakage, bleeding tendency and liver involvement. We studied the histopathological features of a fatal case of dengue-3 vir...

Hantavirus pulmonary syndrome (HPS) was first recognized in 1993 after an outbreak of acute respiratory failure in young people in the Four Corners area of southwestern United States (U.S.). The case fatality rate among these cases was 76% [1]. Fortunately, recent Centers for Disease Control and Prevention (CDC) surveillance data reports a decline in the case-fatality rate of 30 to 40% [2]. HPS...

BACKGROUND AND PURPOSE The Cilostazol Stroke Prevention Study II has shown a similar efficacy in stroke prevention but markedly fewer hemorrhagic events with the phosphodiesterase inhibitor cilostazol versus aspirin. The purpose of this study is therefore to investigate how cilostazol affects cerebral hemodynamics and whether it prevents hemorrhagic transformation induced by recombinant tissue ...

Acalculous hemorrhagic cholecystitis is a rare complication of acute cholecystitis and is associated with a high mortality rate. Magnetic resonance imaging (MRI) is usually not performed for the diagnosis of acute cholecystitis, but it is a valuable imaging modality and affords excellent tissue contrast for the diagnosis of hemorrhagic cholecystitis and the detection of hematoma within the gall...

Acute hemorrhagic leukoencephalitis (AHLE) is a rare demyelinating disease characterized by an acute rapidly progressive fulminant inflammation of the white matter. In this case report, we introduce a case of AHLE in children with an interesting and lengthy process and successful treatment.A previously healthy 13-year-old girl was admitted to the hospital because of fever and loss of consciousn...

BACKGROUND Acute myringitis is an inflammation of the tympanic membrane that occurs alone or in association with external otitis or otitis media. The two clinical entities, based on physical examination, are bullous myringitis and hemorrhagic myringitis. OBJECTIVES To investigate the association of concomitant middle ear disease with acute myringitis and to analyze the bacteriologic findings ...