At present, Alzheimer disease has no effective treatment due to its complex pathophysiology, which is not yet completely understood. However, abnormal cholinergic function has been shown to play an important role in the many types of brain neurotransmitter dysfunction found in Alzheimer patients. Accordingly, cholinesterase inhibitors that strengthen cholinergic neurotransmission, including gal...

To cite: Catho G, Ader F, Chidiac C, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013008594 DESCRIPTION A 56-year-old woman with a history of eczematis and autoimmune hypothyroidism presenting with superficial bacterial abscess located in the upper medial quadrant of the right breast. Pristinamycine (antistaphylococcal antibiotic available in France, th...

Acute generalized exanthematous pustulosis is a rare drug-induced eruption that characterized by sterile non-follicular pustules arising on an often edematous diffuse erythematous background. Generalized pustular psoriasis acute and severe clinical form of presenting as with base. Differentiating both diseases challenging because their histopathological similarities. A 62-year-old woman present...

The association of chloroquine and proguanil is widely used for antimalarial prophylaxis in Plasmodium falciparum – endemic countries with limited to moderate chloroquine resistance [1]. We report the 1st case of acute generalized exanthematous pustulosis (AGEP) due to this drug combination. A 34-year-old woman with a previous history of maculopapular skin rash induced by mefloquine in 1995 was...

Acute generalized exanthematous pustulosis (AGEP) is a rare disease that has been linked to certain drugs, such as antibiotics, antifungal agents, anticonvulsants, and antihypertensive agents. Other possible triggers that have been described include infection, pregnancy, allergens, spider bites, iodinated contrast media, herbal medicinal products, and tumors. In some cases, however, the causati...

reported to be as high as 69%.[1] Common cutaneous adverse effects include maculopapular eruptions and erythematous eruptions. Toxic epidermal necrolysis, Stevens–Johnson syndrome and acute generalized exanthematous pustulosis have also been reported with the use of imatinib. Other reported cutaneous adverse effects include: hypopigmentation, lichenoid reactions, pityriasiform eruptions, purpur...

Acute generalized exanthematous pustulosis (AGEP) is a rare disease that has been linked to certain drugs, such as antibiotics, antifungal agents, anticonvulsants, and antihypertensive agents. Other possible triggers that have been described include infection, pregnancy, allergens, spider bites, iodinated contrast media, herbal medicinal products, and tumors. In some cases, however, the causati...