Optimal therapy for acute lower extremity deep venous thrombosis (DVT) remains an enigma. While clinical trials demonstrate noninferiority with oral anti-Xa inhibitor, or direct anticoagulant (DOAC), versus combined low-molecular-weight heparin and vitamin K agonist (VKA), the most effective regimen to be determined. This study is a single-center retrospective review conducted from October 2014...

Deep venous thrombosis (DVT) and pulmonary embolism (PE) are serious and costly complications of total hip and knee replacement surgery. The risk of these complications is significantly reduced by prophylaxis. Low molecular weight heparins (LMWH) are being used for this indication with increased frequency. The objective of this study was to assess the cost implications of LMWH for the preventio...

Background: Reported cases of Intraductal papillary mucinous neoplasm (IPMN) are becoming more and frequent. The risk hypercoagulability associated with IPMN is not clearly established in the literature as it was only reported four cases. Therefore, we present a unique case patient who subsequently developed acute pulmonary embolism (PE) deep venous thrombosis (DVT). Case presentation: A 70-yea...

Purpose: To explore the efficacy and safety of the mechanical thrombectomy device AngioJetTM for the treatment of acute deep venous thrombosis (DVT). Methods: A total of 14 patients with DVT undergoing percutaneous mechanical thrombectomy (PMT) between January 2016 and September 2016 were included. PMT was performed after a temporary inferior vena cava filter was implanted. Thrombus clearance w...

Case: A 68-year-old woman presented to our emergency room with subjective fevers, non-productive cough and severe pain in the right lower extremity. Of note, she had sustained a right patellar fracture 6 weeks earlier, treated with a brace. Physical examination showed right lower extremity swelling. Subsequently, she was diagnosed with extensive right deep venous thrombosis (DVT). Local thrombo...

IMPORTANCE OF THE FIELD Anticoagulation is the main therapy for acute deep vein thrombosis (DVT) of the limbs. Over the last five decades, there has been little progress in the development of oral anticoagulant therapies. More recently, we have been experiencing a rapidly changing situation thanks to the development of new orally active anticoagulants. AREAS COVERED IN THIS REVIEW The aim of ...

BACKGROUND Aggressive and early thrombus removal strategy has been widely used as a treatment for iliofemoral deep vein thrombosis (DVT). We compared the long-tem venous outcome, including postthrombotic syndrome (PTS), in patients undergoing catheter-directed thrombolysis (CDT) and pharmacomechanical thrombectomy (PMT). METHODS From January 2009 to December 2013, 61 patients with acute proxi...

Important predictors of adverse outcomes of thrombosis in children, including postthrombotic syndrome (PTS), have recently been identified. Given this knowledge and the encouraging preliminary pediatric experience with systemic thrombolysis, we sought to retrospectively analyze our institutional experience with a thrombolytic regimen versus standard anticoagulation for acute, occlusive deep ven...