BACKGROUND Immuno-compromised patients such as those undergoing cancer chemotherapy are susceptible to bacterial infections leading to biofilm matrix formation. This surrounding biofilm matrix acts as a diffusion barrier that binds up antibiotics and antibodies, promoting resistance to treatment. Developing non-invasive imaging methods that detect biofilm matrix in the clinic are needed. The us...

BACKGROUND The observation of ultrasound generated cavitation bubbles deep in tissue is very difficult. The development of an imaging method capable of investigating cavitation bubbles in tissue would improve the efficiency and application of ultrasound in the clinic. Among the previous imaging modalities capable of detecting cavitation bubbles in vivo, the acoustic detection technique has the ...

We demonstrate submicron resolution imaging using picosecond acoustic phonon pulses. High-frequency acoustic pulses are generated by impulsive thermoelastic excitation of a patterned 15-nm-thick metal film on a crystalline substrate using ultrafast optical pulses. The spatiotemporal diffracted acoustic strain field is measured on the opposite side of the substrate, and this field is used in a t...

This paper is devoted to mathematical modelling in photo-acoustic imaging of small absorbers. We propose a new method for reconstructing small absorbing regions inside a bounded domain from boundary measurements of the induced acoustic signal. We also show the focusing property of the backpropagated acoustic signal. Indeed, we provide two different methods for locating a targeted optical absorb...

Diagnostic ultrasound (US) is safer, quicker and cheaper than other diagnostic imaging modalities. Over the past two decades, the applications of US imaging has been widened due to the development of injectable, compressible and encapsulated microbubbles (MBs) that provide an opportunity to improve conventional echocardiographic imaging, blood flow assessment and molecular imaging. The encapsul...

Acoustic cavitation is investigated experimentally and theoretically starting with a single bubble in an acoustic field. The single bubble is trapped in an acoustic resonator and observed by high-speed imaging and acoustic measurements following its transient dynamics to a possible steady state after generation by laser light. Numerical calculations are done to explore the regions of survival f...

diesel exhaust particles are a complex mixture of thousands of gases and fine substances that contain more than 40 different environmental contaminants. being exposed to these exhaust particles (called soot) can cause lung damage and respiratory problems. diesel particulate filters are used in many countries for mobile sources as a legal obligation to decrease harmful effect of these fine parti...

A simultaneous photoacoustic (PA) tomography imaging technique in multilayer samples was developed. Instead of using the PA image reconstruction methods on the basis of complex algorithms, obtaining a two-dimensional PA image in real time is available by using an acoustic lens that has the ability of parallel imaging. The imaging system can acquire the complete PA signals of high signal-to-nois...