Introduction.?In a paper on the gastric acidity in cholera convalescents Pasricha and others (1940) found that 36 per cent of cases had achlorhydria, 52 per cent a low acid content, and 12 per cent a normal curve; none had hyperchlorhydria or even a high normal curve. They made three suggestions for the cause of this low acidity in their series, namely (a) that it might be the result of acute g...

A simple sensing ensemble was designed to discriminate structurally similar divalent metal chlorides utilizing multivariate data analysis. The system features the binding of four synthesized coumarin-enamine probes to a series of ten metal chlorides. Linear discriminant analysis (LDA) achieves what univariate data analysis alone cannot i.e., full analyte discrimination and differentiation.

A well-defined N-heterocyclic carbene-palladium(II)-1-methylimidazole [NHC-Pd(II)-Im] complex 1 was found to be an effective catalyst for the Mizoroki-Heck reaction of a variety of aryl chlorides with styrenes. Both activated and deactivated aryl chlorides work well to give the corresponding coupling products in good to excellent yields by using tetrabutylammonium bromide (TBAB) as the ionic li...

Abstr&---A general valence force field for secondary chlorides has been refined which includes torsional force constants based on assignments of low frequency modes in model compounds. This force field also incorporates force constants related to observed intermolecular interactions. The good agreement between observed and calculated frequencies indicates that this force field will be useful in...

This study documents that chlorinated analogs of leukotoxin diol 1, in which the vic-diol has been replaced with vic-chlorides (2), induce caspase 3 activity and apoptosis on HepG2 cells in a dose-dependent manner in analogy to the parent diol. This suggests that chlorides may substitute for hydroxyls in certain lipids as bioisosteres in defined biological settings.