The differential diagnoses for acid-base problems can be reduced to a workable few by using a minimal amount of laboratory data. Following well-established principles and formulas, the presenter will help you resolve common acidbase problem cases. • Identify etiologies of anion gap and non-anion gap acidosis. • Explain the principle of osmolar gap. • Differentiate the causes of acid-base distur...

2011;32;240 Pediatrics in Review Mara Nitu, Greg Montgomery and Howard Eigen Acid-Base Disorders http://pedsinreview.aappublications.org/content/32/6/240 located on the World Wide Web at: The online version of this article, along with updated information and services, is l.pdf http://pedsinreview.aappublications.org/http://pedsinreview.aappublications.org/content/32/11/501.1.ful An erratum has ...

The body’s ability to maintain acid-base homeostasis is based on a complex set of interactions between the respiratory and metabolic systems. This article reviews normal acid-base physiology and examines disorders of acid-base imbalances, first within a primary metabolic cause and then within a primary respiratory cause. Covering the complex nuances of acid-base control within a limited-scope r...

I read the interesting article by Zampieri and colleagues [1] reporting the new association between inflammatory cytokines and acid-base components in 87 ICU patients. I would like to note that whatever approach is used to investigate the acid-base status (the celebrated bicarbonate-centered approach, the base excess methodology or the physicochemical approach) most of the acidbase parameters h...

AIMS To test the hypothesis that alterations in acid base or calcium concentration may affect proinsulin processing or the insulin secretion mechanism. METHODS Changes in proinsulin secretion or cleavage were assessed by measuring serum intact proinsulin and immunoreactive insulin concentrations in three models of acid base and calcium disturbance: (1) subacute changes in acid base status in ...

Disturbances of acid-base balance and electrolyte abnormalities are commonly seen in patients with acute leukemia. Our study aimed at illuminating the probable pathogenetic mechanisms responsible for these disturbances in patients with acute leukemia admitted to our hospital. We studied 66 patients (24 men and 44 women) aged between 17 and 87 years old on their admission and prior to any therap...