Acetobacter suboxydans is known to bring about oxidation of polyhydroxy compounds. The action of the bacterial enzyme is limited, however, to substances with specific configurations. According to the generalization of Bertrand,’ only those hydroxyl groups are oxidized which are situated between a primary hydroxyl group and a secondary one in a cis position. Hann, Tilden, and Hudson,2 in a compa...

Acetobacter suboxydans is known to bring about oxidation of polyhydroxy compounds. The action of the bacterial enzyme is limited, however, to substances with specific configurations. According to the generalization of Bertrand,’ only those hydroxyl groups are oxidized which are situated between a primary hydroxyl group and a secondary one in a cis position. Hann, Tilden, and Hudson,2 in a compa...

Streptococcus gallolyticus subspecies (subsp.) gallolyticus (formerly bovis biotype I) bacteremia has been associated with colonic adenocarcinoma. The bovis species underwent reclassification in 2003. Subtypes of gallolyticus are associated with colonic malignancy but are less frequent, resulting in less awareness. A 71-year-old male admitted with worsening lower back pain and fevers. Initial v...

It has been shown that glycerol can be oxidized beyond the dihydroxyacetone (DHA) stage by resting Acetobacter suboxydans cells (1). Through washing and centrifuging of the cells at room temperature, most of the oxidative activity was destroyed, which, however, could be restored by the addition of inorganic phosphate and diphosphopyridine nucleotide (DPN). 2,4-Dinitrophenol (DNP), a phosphate “...

D-Sorbitol and dulcitol (galactitol), which, together with D-mannitol, are the three naturally occurring hexitols, have been known since the last quarter of the nineteenth century. Many fungi can utilize sorbitol for growth, but dulcitol is assimilated poorly by Aspergillus niger and a few yeasts. Among bacterial fermentations of these hexitols the best known are those by members of the Acetoba...

BACKGROUND Acetobacter sp. CCTCC M209061 could catalyze carbonyl compounds to chiral alcohols following anti-Prelog rule with excellent enantioselectivity. Therefore, the enzymatic characterization of carbonyl reductase (CR) from Acetobacter sp. CCTCC M209061 needs to be investigated. RESULTS A CR from Acetobacter sp. CCTCC M209061 (AcCR) was cloned and expressed in E. coli. AcCR was purified...