Background: ABO-incompatible human leukocyte antigen (HLA)-matched platelets are used to manage thrombocytopenic patients with anti-HLA-A and/or anti-HLA-B (HLA-A/B) antibodies when ABO-identical donors are not available. This study assessed the effectiveness of ABO-incompatible HLA-matched platelets in an unselected group of patients with acute myeloid leukaemia (AML) undergoing cytotoxic chem...

Receptor for advanced glycation end-products (RAGE) is a marker of alveolar type I cells and is elevated in the pulmonary edema fluid of patients with acute lung injury (ALI). We tested the hypothesis that RAGE in the bronchoalveolar lavage (BAL) would be elevated in experimental models of direct ALI characterized by alveolar epithelial cell injury. We developed ELISA measurements for RAGE and ...

INTRODUCTION Acute lung injury (ALI) can result from various insults to the pulmonary tissue. Experimental and clinical data suggest that spontaneous breathing (SB) during pressure-controlled ventilation (PCV) in ALI results in better lung aeration and improved oxygenation. Our objective was to evaluate whether the addition of SB has different effects in two different models of ALI. METHODS F...

BACKGROUND A new formulation of a botulinum neurotoxin type A (BoNTA-ABO; Dysport [abobotulinumtoxinA]; Medicis Aesthetics, Scottsdale, AZ) was recently approved by the US Food and Drug Administration for the treatment of moderate to severe glabellar lines. OBJECTIVE This article summarizes the safety data from five phase III clinical trials investigating the use of BoNTA-ABO in the treatment...

Broad research interests and related applications: My research is in the area of stochastic systems, computational methods for sensing, estimation, and control problems, with a focus on robotic systems. In real-world systems, uncertainty (both in the system model and sensory readings) is omnipresent. A few of the vast set of applications for this research include (i) Motion planning for mobile ...

| 2017 | 1 Seyed-Hossein Abtahi1,2, Mohammad-Ali Abtahi1,2, Seyed Ali Akbar Mortazavi1,2, Hamidreza Jahanbani-Ardakani2,3,4, Mehdi Mazloumi5 1Department of Ophthalmology, School of Medicine, Isfahan University of Medical Sciences, 2Isfahan Eye Research Center, Isfahan University of Medical Sciences, 3Medical School, Isfahan University of Medical Sciences, 4Isfahan Medical Students Research Cent...

OBJECTIVE The aim of the study was to determine blood groups and Rhesus factor from dentin and pulp using absorption-elution (AE) technique in different time periods at 0, 3, 6, 9 and 12 months, respectively. MATERIALS AND METHODS A total of 150 cases, 30 patients each at 0, 3, 6, 9 and 12 months were included in the study. The samples consisted of males and females with age ranging 13-60 yea...

The influence of blood group types on development of brain tumors is unclear since there are conflicting reports from surveys regarding the distribution of ABO blood groups and primary intracranial neoplasms. The present descriptive, retrospective study was therefore made of 907 patients with reliable records for ABO blood groups and proven histological diagnosis who were hospitalized with brai...

Pure red cell aplasia (PRCA) following allogeneic hematopoietic stem cell transplantation (HSCT) has been mostly reported in situations involving major ABO incompatibility between donor and recipient. Conventional treatments such as plasma exchange, erythropoietin, and steroid are often unsatisfactory. Rituximab has been reported to be highly effective for PRCA following major ABO-incompatible ...

Donor shortage remains the single most important factor limiting the success of transplantation medicine. In face of this unrelenting pressure, otherwise prohibitive immunological barriers are increasingly accepted, such as ABO incompatibility of a kidney from an available living donor. Treatment protocols for such situations involve varying combinations of B-cell depletion, removal of isohemag...