Gingival fibromatosis (GF) is characterized by a slow and progressive proliferation that can affect the marginal attached gingiva, or inter-dental papillae. This condition be localized generalized, with varying degrees of severity.GF may develop in susceptible individuals as side effect systemic medications idiopathic gingival fibromatosis. It also related to hereditary factors occurs non-syndr...

Fibromatosis is a rare disease with benign histology. Its infiltrative growth pattern may prevent complete resection. We report a case of a 40-year-old woman with fibromatosis of the neck requiring an emergency operation for acute upper airway obstruction. Gross residual tumour was left behind but excellent tumour shrinkage was achieved by using weekly low-dose methotrexate and vinblastine. Des...

Background. Desmoid fibromatosis (DF) is a rare mesenchymal tumor with invasive growth, high relapse rate, and low incidence (24 cases per 1 million people year). Given the small number of patients DF and, as result, lack knowledge this disease, search for molecular predictors disease course individualization treatment prevention relevant.
 Aim. To study cells' genetic immunohistochemical ...

BACKGROUND Desmoid-type fibromatosis is defined as an intermediate tumor that rarely occurs in the head and neck of children. There is no doubt as to the value of complete surgical excision for desmoid-type fibromatosis. However, in pediatric patients, surgeons may often be concerned about making a wide excision because of the potential for functional morbidity. Some studies have reported a lac...

Dupuytren's disease (palmar fibromatosis) involves nodules in fascia of the hand that leads to flexion contractures. Ledderhose disease (plantar fibromatosis) is similar with nodules of the foot. While clinical aspects are well-described, genetic mechanisms are unknown. We report a family with cardiac disease due to a heterozygous LMNA mutation (c.736C>T, p.Gln246Stop) with palmar/plantar fibro...

Fibromatosis and/or desmoid tumors which constitute less than 1% of all neoplasms and 3.0% of all soft-tissue tumors are pathologically benign proliferations of the fibroblasts but are locally aggressive with infiltrative type of growth and tendency toward recurrence. Bilateral symmetrical perirenal involvement has been described in many conditions which can be renal, subcapsular, or perirenal ...