نتایج جستجو برای: abcc1

تعداد نتایج: 519  

2014
Annamaria Ruzzo Francesco Graziano Fabio Galli Elisa Giacomini Irene Floriani Francesca Galli Eliana Rulli Sara Lonardi Monica Ronzoni Bruno Massidda Vittorina Zagonel Nicoletta Pella Claudia Mucciarini Roberto Labianca Maria Teresa Ionta Enzo Veltri Pietro Sozzi Sandro Barni Vincenzo Ricci Luisa Foltran Mario Nicolini Edoardo Biondi Annalisa Bramati Daniele Turci Silvia Lazzarelli Claudio Verusio Francesca Bergamo Alberto Sobrero Luciano Frontini Mauro Magnani

We investigated 17 polymorphisms in 11 genes (TS, MTHFR, ERCC1, XRCC1, XRCC3, XPD, GSTT1, GSTP1, GSTM1, ABCC1, ABCC2) for their association with the toxicity of fluoropyrimidines and oxaliplatin in colorectal cancer patients enrolled in a prospective randomized trial of adjuvant chemotherapy. The TOSCA Italian adjuvant trial was conducted in high-risk stage II-III colorectal cancer patients tre...

Journal: :Journal of medicinal chemistry 2012
Raffaella Zoe Pellicani Angela Stefanachi Mauro Niso Angelo Carotti Francesco Leonetti Orazio Nicolotti Roberto Perrone Francesco Berardi Saverio Cellamare Nicola Antonio Colabufo

The multifactorial nature of chemotherapy failure in controlling cancer is often associated with the occurrence of multidrug resistance (MDR), a phenomenon likely related to the increased expression of members of the ATP binding cassette (ABC) transporter superfamily. In this respect, the most extensively characterized MDR transporters include ABCB1 (also known as MDR1 or P-glycoprotein) and AB...

Journal: :Reviews in agricultural science 2022

In farm animals, both genetic and non-genetic factors affect reproductive traits. These can be categorized as intrinsic extrinsic. Extrinsic relate to the animal’s environment, while are related its genotype. Various traits studied concerning age, season, management, nutrition, body score, birth type. addition, variations of transforming growth factor-β (TGFβ) superfamily including BMPR-1B, BMP...

2014
Shiv Poojan Anupam Dhasmana Qazi Mohammad Sajid Jamal Mohd Haneef Mohtashim Lohani

Arsenic is the most toxic metalloid present in the natural environment in both organic and inorganic arsenic forms. Inorganic arsenic is often more hazardous than the organic form. Arsenite and arsenate compounds are the major inorganic forms which are toxic causing severe human health dysfunction including cancer. Excretion of arsenic from the system is found elusive. Therefore, it is of inter...

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