BACKGROUND Few data exist on gender-related differences in clinical presentation, diagnostic findings, management, and outcomes in acute aortic dissection (AAD). METHODS AND RESULTS Accordingly, we evaluated 1078 patients enrolled in the International Registry of Acute Aortic Dissection (IRAD) to assess differences in clinical features, management, and in-hospital outcomes between men and wom...

Alterations in the diversity of the gut microbiota are believed to underlie the development of antibiotic-associated diarrhea (AAD). A molecular phylogenetic analysis was performed to document temporal changes in the diversity of fecal bacteria of a patient who developed AAD. Antibiotic administration was associated with distinct changes in the diversity of the gut microbiota, including a marke...

Objective. The objective of this study is to evaluate the cost-effectiveness of catheter ablation for rhythm control compared to antiarrhythmic drug (AAD) therapy in patients with atrial fibrillation (AF) who have previously failed on an AAD. Methods. An economic model was developed to compare (1) catheter ablation and (2) AAD (amiodarone 200 mg/day). At the end of the initial 12 month phase of...

Abstract Objectives The relationship between inflammatory cytokines and postoperative delirium (POD) remains to be further investigated, especially in patients undergoing acute type A aortic dissection (AAD). Interleukin-6 (IL-6) is involved the process has recently been identified as a biomarker of cerebral dysfunction. We explored hypothesis that IL-6 was one critical causes POD after surgica...

We recently published a study in which we showed that acute aortic dissection (AAD) is often initially missed, which was contributable to the absence of a typical clinical profile [1]. In addition to our findings, Siniorakis and colleagues stress the importance of fever as an often overlooked sign of AAD. The body temperature on admission was not incorporated in our database, as such we cannot ...

The modified square well Potential is combined with perturbed-hard-trimer-chain (PHTC) EOS to predict the solubility parameter of several fluids including alkanes, refrigerants and molten polymers. The performance of the proposed model has been evaluated by predicting the solubility parameter of 12 hydrocarbons,3 refrigerants, and 12 polymers. From the 263 data points for hydrocarbons and refri...

Tissue-Specific Inactivation of Type 2 Deiodinase Reveals Multilevel Control of Fatty Acid Oxidation by Thyroid Hormone in the Mouse. Diabetes 2014;63:1594–1604 DOI: 10.2337/db14-er08 Tatiana L. Fonseca, Joao Pedro Werneck-De-Castro, Melany Castillo, Barbara M.L.C. Bocco, Gustavo W. Fernandes, Elizabeth A. McAninch, Daniele L. Ignacio, Caio C.S. Moises, Alexandre Ferreira, Balázs Gereben, and A...

BACKGROUND Acute kidney injury (AKI) is common after surgery for acute aortic dissection (AAD) and increases in-hospital and long-term mortality. However, few data exist on the clinical and prognostic relevance of early preoperative AKI in patients with type A AAD. We aimed to determine the incidence and predictors of preoperative AKI and the impact of AKI on in-hospital outcomes in patients wi...

BACKGROUND Modifiable lifestyle-related factors associated with risk of abdominal aortic aneurysm (AAA) are rarely investigated with a prospective design. We aimed to study possible associations among such factors and comorbidities with mean abdominal aortic diameter (AAD) and with risk of AAA among men screened for the disease. METHODS AND RESULTS Self-reported lifestyle-related exposures we...

Background: Atrial Fibrillation is the most common cardiac arrhythmia. It increases the risk of thromboembolic events and many atrial fibrillation patients suffer quality of life impairment due to disturbed heart rhythm. Pulmonary vein isolation using radiofrequency catheter ablation treatment is aimed at maintaining sinus rhythm ultimately improving quality of life. Randomized clinical trial h...