OBJECTIVES To examine the clinical utility of the first-trimester markers of aneuploidy in their ability to predict future fetal loss. METHODS We examined 54,722 singleton pregnancies with no chromosomal abnormality and with complete outcome data that had undergone screening for trisomy 21 by a combination of fetal nuchal translucency (NT) thickness, maternal serum free beta-human chorionic g...

BACKGROUND/AIM Pregnancy-associated plasma protein A (PAPP-A) is high molecular matrix metalloproteinase originally isolated in the serum of pregnant women. The aim of this study was to analyze the values of concentration of PAPP-A in assessment of progress and outcome of pregnancy in pregnant women diagnosed with threatening preterm delivery, preeclampsia and fetal growth restriction in relati...

Two new species of the genus Cratospila Foerster, 1863 (Braconidae: Alysiinae), albosignata sp. nov. and C. longivena , are described illustrated. In addition, DNA barcode region mitochondrial cytochrome c oxidase subunit I ( COI ) both has been sequenced with three previously albifera luteocephala syntoma ). Alysia ponerola Papp, 2009 which was recorded from North Korea is transfered in (Papp,...

STUDY QUESTION Can independent predictors of pregnancy-associated plasma protein-A (PAPP-A) levels be identified in a group of women who conceived following IVF/ICSI? SUMMARY ANSWER The significantly decreased PAPP-A level in IVF and ICSI pregnancies compared with non-IVF/ICSI pregnancies was correlated strongly with the serum estradiol (E2) level at ovulation triggering. WHAT IS KNOWN ALRE...

Background: Prenatal detection of genetic abnormalities is one the biggest challenges current fetal medicine. screening for chromosomal can be done using biochemical tests. The a risk estimation test and not diagnostic test. Methods: Statistical data treatment had been performed on sample 362 pregnant women prenatal screening. This was retrospective analysis study undertaken at National Referen...

OBJECTIVES To determine the levels of first-trimester free beta-human chorionic gonadotrophin (free betahCG), pregnancy-associated plasma protein A (PAPP-A) and nuchal translucency (NT) in twin pregnancies. METHODS The study included 93 patients with twin pregnancy and 4,977 with singletons who underwent first-trimester testing using free betahCG, PAPP-A and NT at 10-13 weeks of gestational a...