The cost of answering a query against an ontology is affected by at least three elements: the size of the ontology, the strategy followed to combine the data, and the order or plan in which data is processed. In the context of the Semantic Web, very large ontologies have been defined; therefore, techniques to identify efficient evaluation strategies are needed. We propose cost-based optimizatio...

OBJECTIVE To summarise all meta-analyses of randomised controlled trials that have evaluated the effects of exercise therapy on functional capacity in patients with chronic diseases. DESIGN Umbrella review of meta-analyses of randomised controlled trials. DATA SOURCES We systematically searched the CENTRAL, CINAHL, DARE, Medline, OTSeeker, PEDro, SPORTDiscus, ProQuest Nursing & Allied Healt...

AIM Our goal wasto produce a field synopsis of genetic associations with preterm birth and to set up a publicly available online database summarizing the data. METHODS We performed a systematic review and meta-analyses to identify genetic associations with preterm birth. We have set up a publicly available online database of genetic association data on preterm birth called PTBGene (http://ric...

background: intravenous immunoglobulin (ivig) is an established treatment of immune mediated demyelinating neuropathy including guillain-barré syndrome and chronic inflammatory demyelinating polyneuropathy. recent trials suggest its efficacy in treating relapsing- remitting multiple sclerosis. ivig exerts a number of effects, which may be beneficial in treating multiple sclerosis (ms): reductio...

background: intravenous immunoglobulin (ivig) is an established treatment of immune mediated demyelinating neuropathy including guillain-barré syndrome and chronic inflammatory demyelinating polyneuropathy. recent trials suggest its efficacy in treating relapsing- remitting multiple sclerosis. ivig exerts a number of effects, which may be beneficial in treating multiple sclerosis (ms): reductio...

Reformatting information currently held in databases into HyperText Markup Language (HTML) pages suitable for the World-Wide Web (WWW) requires significant effort both in creating the pages initially and their subsequent maintenance. We avoid these costs by directly coupling a WWW server to the source data within a database using additional software we have developed. This software layer automa...