Bee venom is a rich source of pharmacologically active substances. In this study, we identified a bumblebee (Bombus ignitus) venom Kunitz-type serine protease inhibitor (Bi-KTI) that acts as a plasmin inhibitor. Bi-KTI showed no detectable inhibitory effect on factor Xa, thrombin, or tissue plasminogen activator. In contrast, Bi-KTI strongly inhibited plasmin, indicating that it acts as an anti...

We present a bi-objective model for a green truck scheduling and routing problem at a cross-docking system. This model determines three key decisions at the cross dock: (1) defining a sequence and schedule of inbound trucks at the receiving door, (2) specifying a sequence and a schedule of outbound trucks at the shipping door, and (3) determining the routes of the outbound truck while serving c...

Many organizations have recognized the importance of increasing commitment towards delivering longterm success of Business Intelligence (BI). However, effective BI strategies and governance to accommodate the rapid growth of data volumes are still scarce. Furthermore, there appears to be low usage rates of BI and analytics among business users. Consequently, many organizations are still positio...

In this paper, the propagation of electromagnetic waves through an infinite slab of uni- or bi- axial chiral medium is analytically formulated for an arbitrary incidence using 4×4 matrix method. In this powerful method, a state vector differential equation is extracted whose solution is given in terms of a transition matrix relating the tangential components of electric and magnetic fields at t...

Deadlock-free routing algorithms have been developed recently without fully understanding the frequency and characteristics of deadlocks. Using a simulator capable of true deadlock detection, we measure a network’s susceptibility to deadlock due to various design parameters. The effects of bidirectionality, routing adaptivity, virtual channels, buffer size and node degree on deadlock formation ...

1 Analysis of DNA Chains by Means of Factorial Moments Huijie Yang Fangcui Zhao Physics Institute, Hebei University of Technology, Tianjin 300130, China Yizhong Zhuo Xizhen Wu China Institute of Atomic Energy, Beijing 102413, P.O.X 275(18), China Abstract By means of the concept of factorial moments we examine DNA sequences from yeast to distinguish coding and non-coding regions. It is found th...

In spite of its potential for bidirectionality, Extensible Dependency Grammar (XDG) has so far been used almost exclusively for parsing. This paper represents one of the first steps towards an XDG-based integrated generation architecture by tackling what is arguably the most basic among generation tasks: lexicalization. Herein we present a constraint-based account of disjunction in lexicalizati...

A method for stochastically modeling bidirectionality in chart parsing is presented. A bidirectional parser, which starts analysis from certain dynamically determined positions of the sentence (the islands), has been built. This island-driven parser uses the stochastic model to guide the recognition process. The system has been trained and tested over two wide-coverage corpus: Spanish Lexesp an...

A framework to develop proactive BI is presented and discussed in this chapter. In a proactive process, analysis develops as a scientific investigation or research, where analysts must discover an initial set of hypotheses and then test or evaluate the hypotheses. The steps of the framework are presented and ways to perform each step are discussed. Data mining techniques are associated to this ...