The present study aimed to reveal the expression of STAT3 and Anxa 2 in CRC specimens and to investigate the effects of STAT3 and Anxa 2 signaling on the proliferation, invasion, and migration in CRC Caco-2 cells. Results demonstrated that both Anxa 2 and STAT3 were highly expressed in CRC specimens in both mRNA and protein levels, with or without phosphorylation (Tyrosine 23 in Anxa 2 and Tyro...

Introduction. Quality assessment of medical student’s knowledge and way of practical and laboratory teaching is one of the priority studies in medical Education. The aim of this study is going over these skills in different majors of Babol Medical University, in order to improve the Quality and Circumstances of education. Methods. This descriptive- analytical study was performed as cross-secti...

INTRODUCTION Late HIV diagnosis is common and associated with an increased risk of clinical progression, blunted immune response on antiretroviral (ARV) therapy and higher risk of drug toxicity. Across Europe, more than a third of patients are diagnosed late and consequently delay medical care. European Consensus definition group identify as late presentation (LP) persons, presenting for care, ...

Abstract Study question Are the gene variants involved in meiosis initiation responsible for premature ovarian insufficiency (POI)? Summary answer MEIOSIN variant participates pathogenesis of human POI by impairing due to insufficient transcriptional activation essential meiotic genes. What is known already Meiosis key event establishment reserve, and several defects homologous recombination ha...

OBJECTIVE The contribution of smoking to socioeconomic inequalities in health is increasing worldwide, including in Brazil. Youth smoking may play an important role in the increasing social inequalities related to smoking. This study investigates social determinants of smoking among 15-year-old to 19-year-old individuals. DESIGN Cross-sectional study. SETTING The study uses data of 3536 par...