OBJECTIVES To compare the results of clinical and pathological staging for a large cohort of patients with head and neck squamous cell carcinoma (HNSCC) and to examine patterns and ramifications of the disparity between staging methods. DESIGN Prospective inception cohort (median follow-up, 7 years). SETTING Multi-institutional cooperative group study (Eastern Cooperative Oncology Group 439...

The Pretreatment Extent of Disease System (PRETEXT) was designed for childhood liver tumors. The aim of this study was to confirm the prognostic value of the PRETEXT staging system compared with the currently and commonly used staging systems of hepatocellular carcinoma (HCC) after applying PRETEXT system in patients with HCC who underwent curative partial hepatectomy.Clinical data of consecuti...

1 Wagner B, Patard JJ, Mejean A et al. Prognostic value of renal vein and inferior vena cava involvement in renal cell carcinoma. Eur. Urol. 2009; 55: 452–9. 2 Moch H, Artibani W, Delahunt B et al. Reassessing the current UICC/AJCC TNM staging for renal cell carcinoma. Eur. Urol. 2009; 56: 636–43. 3 Kim HL, Zisman A, Han KR et al. Prognostic significance of venous thrombus in renal cell carcino...

Staging systems aim to describe malignant tumours in a standardized fashion to assist in therapy planning and estimation of prognosis, allow comparison of different therapeutic strategies, facilitate communication between individuals and institutions, improve our knowledge of malignant disease and ultimately improve the outcome for patients. With the continuous increase in data and, ideally, ou...

The preoperative prognostic nutritional index (PNI) may forecast colorectal cancer (CRC) outcomes, but the evidence is not conclusive. Here, we retrospectively analyzed a cohort of patients from the Department of Surgical Oncology at the First Hospital of China Medical University (CMU-SO). We also conducted a meta-analysis of eleven cohort studies. Bayesian Information Criterion (BIC) was used ...

In the 1997 revision of the TNM staging system for lung cancer, patients with T3N0M0 disease were moved from stage IIIA to stage IIB since these patients have a better prognosis. Despite this modification, the local lymph node metastasis remained the most important prognostic factor in patients with lung cancer. The present study aimed to evaluate the prognosis of patients with T3N1 disease as ...