introduction: after presbycusis, noise-induced hearing loss is the second most common cause of acquired hearing loss. numerous studies have shown that high-intensity noise exposure increases free radical species; therefore, use of antioxidants to detoxify the free radicals can prevent cellular damage in the cochlea. we studied the potential hearing protective effect of different doses of ascorb...

BACKGROUND Contrast agents can cause a reduction in renal function that may be due to the generation of reactive oxygen species. Conflicting evidence suggests that administration of the antioxidant acetylcysteine prevents this renal impairment. The action of other antioxidant agents has not been investigated. METHODS AND RESULTS We conducted a randomized, double-blind, placebo-controlled tria...

A study was conducted to determine the additive effects of calcium (Ca) levels and the enzyme phytase, organic acids (citric, ascorbic acid), vitamin D on broiler performance and nutrient digestibility (d 3 1 to 21) in wheat-based diet. Broilers were fed the following diets at either 7.9, or 9 g/kg of dietary Ca with: 1) a negative control wheat-based diet, 3.15 g/kg available phosphorus (P) (N...

THE biochemical action of i-ascorbic acid has hitherto been studied principally on the scorbutic guinea-pig. Only recently Harris et al. [1933] investigated the excretion of ascorbic acid in the human subject and found that with a normal intake of vitamin C about 30 mg. of ascorbic acid can be determined by dichlorophenolindophenol titration in the daily output of urine. The excretion is tempor...

in this study, the essential oil obtained by hydrodistillation of the seeds of vitex pseudo-negundo (verbenaceae), growing wild in sabzevar, khorasan razavi province, iran, were analyzed by gc and gc/ms. the yield of total volatiles was 0.8% (w/w). thirty-seven compounds representing 92.4% of the seed oil were identified. the main components of the oil were hexadecanoic acid (8.0%), elemol (7.0...

Antioxidants present in natural sources help to scavenge free radicals and thus provide health benefits. This study reports in vitro radical scavenging and antioxidant capacity of crude methanol and ethanol-water extracts of the fruits of Tetrapleura tetraptera and Parkia biglobosa. Total phenolic contents in Tetrapleura tetraptera were 147.82±1.36 and 130.33±1.04 mg GAE/g dry weight while that...

disastrous effect of nickel on spinach was discussed by number of authors but the effect of amendments like biochar with nickel on spinacea oleraceal. is not still discussed by any author of the world because biochar was used as soil amendments which play a vital role in reducing mobilization and uptake of nickel by spinach plants.  as nickel contaminated plants are very harmful for the consump...

OBJECTIVE To test whether ascorbic acid supplementation has any cytoprotective effect on a model of secondary biliary cirrhosis in young rats. METHODS We studied 40 Wistar rats weaned at the 21st postnatal day. Each group of 10 was subjected to one of the following four treatments, until 49th postnatal day, when they suffered euthanasia: 1) LC-double ligature and resection of the common bile ...

Among the most important problems of pistachio are physiological disorders such as fruit abscission and production of blank nuts. Environmental stresses and inadequate nutrition during flowering time have increased these problems in recent years. In order to evaluate the effects of foliar treatments with polyamines and other compounds (amino acids and ascorbic acid) on quantitative and qualitat...