In the first randomised controlled trial of naltrexone implants, Kunøe et al identify two inclusion criteria in their methodology: being an in-patient and being 18 years or above. Exclusion criteria are given as psychosis, pregnancy and serious hepatic disease. Of 667 possible participants, 480 are excluded. In the results, the term ‘ineligibility’ is used to describe not completing treatment, ...

Thioredoxin 1 (Trx1) facilitates the reduction of signaling molecules and transcription factors by cysteine thiol-disulfide exchange, thereby regulating cell growth and death. Here we studied the molecular mechanism by which Trx1 attenuates cardiac hypertrophy. Trx1 upregulates DnaJb5, a heat shock protein 40, and forms a multiple-protein complex with DnaJb5 and class II histone deacetylases (H...

Contingent valuation using willingness to pay (WTP) is one of the methods available for assessing the value of a new technology or treatment for a disease in monetary terms. Experience with this method is lacking in epilepsy. The objectives of this study were to assess the acceptability of the WTP method in epilepsy, the level of the responses, and to investigate its validity by comparison with...

This research investigated whether brainstem neural mechanisms that mediate lateralization of sounds can be extracted from the frequency-following response (FFR). Monaural and binaural FFRs were obtained from normal-hearing subjects to low-frequency (500 Hz) linearly gated tone bursts (4-4-4 msec) at 40, 50, and 60 dB SL and four interaural time differences (ITDs) (0, 333, 500, and 667 microsec...

Phytochrome was partially purified from etiolated seedlings of Avena sativa L. Several properties of the red-absorbing (P(R)) and far-red absorbing (P(FR)) forms of the pigment were compared. The 2 forms could not be shown to differ with respect to their sedimentation velocity in sucrose density gradients, elution volume from Sephadex G-200 columns, binding properties on calcium phosphate, or e...

Four chlorophyll-protein complexes have been resolved from the cyanophyte, Nostoc sp., by sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis at 4 C. Complexes solubilized by SDS from Spinacia oleracea were run for comparison. As has been well documented, the P700-chlorophyll a-protein complex from the higher plant and blue-green algal samples are similar, and the light-harvesting p...

In the first randomised controlled trial of naltrexone implants, Kunøe et al identify two inclusion criteria in their methodology: being an in-patient and being 18 years or above. Exclusion criteria are given as psychosis, pregnancy and serious hepatic disease. Of 667 possible participants, 480 are excluded. In the results, the term ‘ineligibility’ is used to describe not completing treatment, ...

Biphenyl has been widely used as a heat-transfer agent, a dye mordant, a synthetic resin, a constituent of agricultural chemicals and a post-harvest fungicide to preserve citrus fruits. Occupational biphenyl poisoning has been characterized by disorders of the liver, kidney, central and peripheral nervous systems and motor and muscle functions. The carcinogenic potential of biphenyl was not eva...

Let ω(·) denote the union of all ω-limit sets of a given map. As the main result of this paper we prove that, for given continuous interval maps f1, . . . , fm, the union of all ω-limit sets of the product map f1 × · · · × fm and the cartesian product of the sets ω(f1), . . . , ω(fm) coincide. This result enriches the theory of multidimensional permutation product maps, i.e., maps of the form F...