Synaptic plasticity in the central nervous system (CNS) of mammals has been discussed for many years. Several forms of synaptic plasticity of mammal’s CNS have been identified, such as those that occur in long-term potentiation (LTP). Different types of LTP have been observed in distinctive areas of the CNS of mammals. The hippocampus is one of the most important areas in the CNS that pla...

introduction: limited data are available on the effectiveness of antidepressants in the treatment of functional gastrointestinal disorders in children. we evaluated the effectiveness of citalopram in the treatment of childhood functional abdominal pain (fap).   material and methods: children with fap (n=115, aged 6-18 years) received either citalopram 20 mg/day or placebo for 4 weeks. treatment...

PURPOSE NADPH oxidase-generated reactive oxygen species (ROS) are implicated in angiogenesis. Isoforms of NADPH oxidase NOX1, NOX2, and NOX4 are reported to be expressed in endothelial cells (ECs). Of these, NOX1 and NOX2 have been reported to contribute to intravitreal neovascularization (IVNV) in oxygen-induced retinopathy (OIR) models. In this study, we tested the hypothesis that the isoform...