ةـصلاخلا : جا تحت زجت ة قيرط س كعلا ىفص نلا نو لل ثحبلا لود ج ة ئ ي طعتو ل قأ باسح تاوطخ ى لإ ي ةد يج جئا تن . دحاو ثحب لودج ة قيرطلا مدختستو اً يُ َّ زخ نُ ، طقف ةءار قلل ةر آاذ ىف و نو للا فيفختل مي ق ى لع لودجلا ىو تحي باسحلا ةقباس ) ىدامرلا ىوتسملا ( ىسكعلا ىفصنلا نوللا تايلمعل . ة يزاوتم باسح ة قيرط حر تقي ثحبلا اذ هو لإ زاجن ىفصنلا نوللا سكعلا ي ، جتب كلذو ىلإ درفنملا ثحبلا لودج ةئز نم ددع...

Cyanobacteria contain several genes, annotated ndh, whose products show sequence similarities to subunits found in complex I (NADH:ubiquinone oxidoreductase) of eubacteria and mitochondria. However, it is still unclear whether the cyanobacterial ndh gene products actually form a single large protein complex or exist as smaller independent complexes. To address this, we have constructed a strain...

BACKGROUND Hypoxia and nitric oxide (NO) play important roles in the onset and progression of glaucoma. Vascular endothelial growth factor (VEGF) is one of the main factors responsive to hypoxia and NO. In this study, we investigated the association between the BstUI C/T VEGF gene polymorphism and primary open angle glaucoma (POAG). METHODS 60 POAG patients and 78 healthy volunteers were enro...

The transport function of the rat type IIa Na(+)/P(i) cotransporter is inhibited after binding the cysteine modifying reagent 2-aminoethyl methanethiosulfonate hydrobromide (MTSEA) to a cysteine residue substituted for a serine at position 460 (S460C) in the predicted third extracellular loop. This suggests that Ser-460 lies in a functionally important region of the protein. To establish a "str...

Cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel belonging to the adenosine triphosphate (ATP)-binding cassette (ABC) superfamily. ABC proteins share a common molecular mechanism that couples ATP binding and hydrolysis at two nucleotide-binding domains (NBDs) to diverse functions. This involves formation of NBD dimers, with ATP bound at two composite interfacial ...