نتایج جستجو برای: 46 to 45

تعداد نتایج: 10661597  

Journal: :Archives of disease in childhood 1979
D C Candy A R Hayward D T Hughes L Layward J F Soothill

Six children, with severe deficiency of some or all of the immunoglobulins and minor somatic abnormalities, had chromosomal abnormalities: (1) 45,XY,t(13q/18q), (2) 46,XY,21ps +, (3) two brothers 46,XY (inv. 7) (4) 45,X,t(11p/10p)/46X,iXq,t(11p/10p) and, (5) in addendum, 45,XX,-18;46,XX, r18. The chromosome abnormalities were detected in B- as well as T-lymphocytes (as evidenced by using both P...

Journal: :Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 2015
Silvano Bertelloni Giampiero I Baroncelli Francesco Massart Benedetta Toschi

45,X/46,XY mosaicism is a rare sex chromosome disorder of sex development. Short stature is a main feature of boys with this condition. Different causes likely contribute to growth impairment. Growth hormone (GH) has been administered to treat short stature in boys with 45,X/46,XY mosaicism, but conflicting data are available. Here, spontaneous growth patterns as well as short- and long-term fo...

Journal: :Genetic testing and molecular biomarkers 2015
Anna-Maria Denes Kerstin Landin-Wilhelmsen Yvonne Wettergren Inger Bryman Charles Hanson

In the normal population, loss of one of the sex chromosomes leading to monosomy (45,X) is a part of the aging process. In Turner syndrome (TS), the classic karyotype 45,X is found in up to 50% at birth, and others have a second cell line; mosaicism. The aim was to study if the chromosomal pattern in TS women changes over time. Fluorescence in situ hybridization was performed on buccal smear ce...

2007
AMANDA MARIE MATHIS Richard R. Tidwell David Wilson Amanda Marie Mathis James E. Hall

....................................................................................45 Introduction .................................................................................46 Materials and Methods ....................................................................49 Results .......................................................................................55

2018
Zhilong Chen Jiangping Song Liang Chen Chaoqun Zhu Hanfang Cai Mingming Sun Allysa Stern Paul Mozdziak Ying Ge Warrie J Means Wei Guo

Titin (TTN) is a major disease-causing gene in cardiac muscle. Titin (TTN) contains 363 exons in human encoding various sizes of TTN protein due to alternative splicing regulated mainly by RNA binding motif 20 (RBM20). Three isoforms of TTN protein are produced by mutually exclusive exons 45 (Novex 1), 46 (Novex 2), and 48 (Novex 3). Alternatively splicing in Novex isoforms across species and w...

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