340 Numerical modeling approaches for multiphase fl ow and tracer or chemical transport in porous media are generally based on methodologies developed for reservoir simulation and groundwater modeling. They involve solving coupled massconservation equations that govern the transport processes of all chemical components in isothermal and nonisothermal subsurface systems using fi nite-difference ...

Invertases, or P-fructofuranosidases, hydrolyze SUC into Fru and Glc. Immobilized acid invertases in plants have been described as localized in the cell wall (Eschrich, 1980; Gogarten, 1986; Sturm and Chrispeels, 1990). Soluble acid invertases were ascribed to the vacuole (Leigh et al., 1979). At least in dicotyledonous plants these organelle-specific isoforms are encoded by separate genes (Stu...

pits, quarries, and on construction sites. The prediction of the penetration rate of drilling machines is very important for cost estimation and planning of rock excavation projects. Many researchers have investigated percussive drilling theoretically or experimentally and correlated the penetration rate with various rock properties. Protodyakonov (1962) developed drop tests and described the c...

The issue of generalizability of clinical trial results has challenged researchers and practitioners of adult cancer patients for years. It is one reason why the adult cancer cooperative group enterprise in the United States is undergoing yet another transformation (1). Figure 1 may capture the essence of the situation. Its foreground shows the most recent data available to this commentator on ...

1 T his article summarizes material presented at the meeting of the American Society of Hypertension (ASH) in New York, New York, May, 2002, as well as presentations at the American Diabetes Association (ADA) Annual Meeting in San Francisco, California, June, 2002. At a symposium addressing the relationships between obesity, hypertension, and cardiovascular disease at the ASH, Roger Unger (Dall...

Accumulation of beta-amyloid (Aβ), neuronal loss and changes in neurotransmitter systems, in particular the cholinergic system, are consistent features of Alzheimer’s disease (AD). Aβ is thought to play a critical role in the pathogenesis of AD and it has therefore become a target of interest as regards a therapeutic approach. The aim of this work was to investigate how different Aβ peptides in...