J. T. Friedlein, Prof. S. E. Shaheen, Prof. R. R. McLeod Department of Electrical Computer and Energy Engineering University of Colorado at Boulder 425 UCB , Boulder , CO 80309 , USA E-mail: [email protected] Prof. S. E. Shaheen Department of Electrical Computer and Energy Engineering University of Colorado at Boulder 425 UCB , Boulder , CO 80309 , USA Prof. G. G. Malliaras Department ...

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The nuclear Dbf2-related protein kinases 1 and 2 (NDR1/2) are closely-related AGC family kinases that are strongly conserved through evolution. In mammals, they are activated inter alia by phosphorylation of an hydrophobic domain threonine-residue [NDR1(Thr-444)/NDR2(Thr-442)] by an extrinsic protein kinase followed by autophosphorylation of a catalytic domain serine-residue [NDR1(Ser-281)/NDR2...

A monoclonal antibody of IgG2a isotype (425) is described that reacts with the epidermal growth factor receptor on human cells of different tissue origins. Monoclonal antibody 425 mediates tumor cytotoxicity in vitro using mouse and human effector cells and suppresses in vivo tumor cell growth of epidermoid (A 431) and colorectal (SW 948) carcinoma-derived cell lines. The tumoricidal effects in...

In the central nervous system, electrogenic sodium- and potassium-coupled glutamate transporters terminate the synaptic actions of this neurotransmitter. In contrast to acidic amino acids, dicarboxylic acids are not recognized by glutamate transporters, but the related bacterial DctA transporters are capable of transporting succinate and other dicarboxylic acids. Transmembrane domain 8 contains...

Hatch, Melvin T. (University of Utah, Salt Lake City), and Paul S. Nicholes. Immunogenic substances in culture filtrates and lysates of Pasteurella tularensis. J. Bacteriol. 88:566-573. 1964.-Culture filtrates and lysates of Pasteurella tularensis were tested for immunogenicity in mice subsequently infected with either strain 425 or 425 F4G. The efficacy of the vaccines varied with dosage and w...

Gestão pública inovadora: um guia para a inovação no setor público. Antônio Isidro. Curitiba: CRV, 2018. 138p. ISBN: 978-85-444- 2566-4. DOI: 10.24824/978854442566.4.