conclusions compared with acarbose or metformin monotherapy, the addition of acarbose to metformin had superior antihyperglycemia efficacy and provided an efficacious and safe alternative for the treatment of type 2 diabetic rats. acarbose/metformin reduced the fasting blood glucose and glycated hemoglobin without significant changes in serum visfatin levels. background diabetes mellitus is a c...

Aim. To investigate the biomechanical effects of zoledronic acid (ZA) on femurs of female osteoporotic rats after follow-up periods of 9 and 12 months. Methods. Eighty female Wistar rats were prospectively assessed. At 60 days of age, the animals were randomly divided into two groups: bilateral oophorectomy (O) (n = 40) and sham surgery (S) (n = 40). At 90 days of age, groups O and S were rando...

[Purpose] This study investigated the effects of visual stimulus using central and peripheral vision fields on postural control. [Subjects and Methods] The subjects consisted of 40 young adult volunteers (15 males, 25 females) who had been informed of the study purpose and procedure. The subjects were randomly divided into four groups of differing visual stimulus. Each group was given visual in...

The purpose of this study was to investigate the effects of mild therapeutic exercise (treadmill) in preventing the inactivity-induced alterations in contractile properties (e.g., power, force, and velocity) of type I soleus single fibers in three different age groups. Young adult (5- to 12-mo-old), middle-aged (24- to 31-mo-old), and old (32- to 40-mo-old) F344BNF1 rats were randomly assigned ...

conclusions it seems that noise pollution has harmful effects on the fertility of males. also these findings may suggest the use of a natural curative approach rather than pharmaceutical drugs to optimize both neuroendocrine gonadal axis and testicular integrity induced by pathogenesis stress, and enhance fertility capacity in men. background this study was conducted to examine the efficacy of ...

Introduction: MicroRNAs have been reported as potentially valuable biomarkers for various ‎diseases, including diabetes, heart diseases, neurological diseases, and age-related diseases. The ‎present study aimed to investigate the effect of 8 weeks of intense intermittent exercise on the ‎expression of mir146a, blood sugar, insulin, and insulin resistance in the hippocampus of aged diabetic male...

Objective. To observe the effect of preventive acupuncture and moxibustion on blood lipid of menopause rats. Methods. Seventy 10-month-old SD rats with estrous cycle disorders were divided into three control groups and four treatment groups (n = 10/group) and another ten 3.5-month-old female SD rats were chosen as young control group. Preventive acupuncture and moxibustion were applied at Guany...

background: recently, there are increasing concerns and interests about the potential effects of electromagnetic field (emf) on both human and animal health. objective: the goal of this study was to evaluate the harmful effects of 50 hz non-ionizing emf on rat oocytes. materials and methods: in this experimental study 30 rats were randomly taken from laboratory animals and their ags and weights...

BACKGROUND CatSper genes are a novel family of four sperm-specific calcium channels, which indicate testis-specific expression patterns. Despite the crucial role of CatSper genes in the male reproduction, very little is known about the factors that regulate their expression. OBJECTIVE The objective of this study was to investigate the effects of vitamin E treatment on the expression of CatSpe...