skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...

The most important mortality and morbidity causes in diabetic patients are coronary, peripheral cerebral diseases. aim of our study was to noninvasively determine dysfunction epicardial coronary arteries microvascular circulation with measurement flow reserve using transthoracic echocardiography type 2 diabetes despite absence ischemic symptoms, demonstrate the amelioration endothelial function...

BACKGROUND Intensive basal-bolus insulin therapy has been shown to improve glycaemic control and reduce the risk of long-term complications that are associated with type 1 diabetes mellitus. Insulin degludec is a new, ultra-longacting basal insulin. We therefore compared the efficacy and safety of insulin degludec and insulin glargine, both administered once daily with mealtime insulin aspart, ...

Ž . The use of a co-extruded soybean poultry by-product meal CEPM and flashed dried poultry Ž . by-product meal FD-PBM was evaluated as replacements for fish meal in a practical diet formulated to contain 32% crude protein and 8% lipid. Each meal was substituted for menhaden Ž fish meal on an iso-nitrogenous basis and offered to juvenile Litopenaeus Õannamei mean initial . Ž wt."S.D., 0.37"0.01...

To examine the effects of ischemic preconditioning on efferent autonomic responses following acute transmural myocardial ischemia/infarction (MI), the time course and extent of efferent sympathetic and vagal denervation were compared between control dogs that received a one-stage sustained coronary occlusion and preconditioned dogs that received four 5-minute coronary occlusions separated by 5 ...

Adherent cells from long-term marrow cultures from 23 individuals were transformed with wild-type simian virus 40 (SV40). After transformation, cloned cell lines were developed that even after rigorous subcloning invariably produced both stromal cells and round cells. The stromal cells expressed cytoskeletal filaments similar to those of long-term marrow culture adherent cells and produced inte...

Background: Copper and zinc in animal diets significantly impact livestock productivity. Zinc is not stored the body must be supplemented regularly to maintain optimal immuno-physiological function animals. Many factors restrict bioavailability of its absorption intestine. Cu deficiency common feed ingredients. Feeding copper levels diet also essential for immune system optimization since inhib...

OBJECTIVES ATP-sensitive potassium channels (K+ATP) prominently contribute to basal coronary tone; however, flow reserve during exercise remains unchanged despite channel blockade with glibenclamide (GLI). We hypothesized that increasing perfusion pulsatility, as accompanies exercise, offsets vasoconstriction from K+ATP-channel blockade, and that this effect is blunted by nitric oxide synthase ...