the synthesis of 1,5-dihydroxy-9,10-anthraquinone (17); (1,5-dha) was accomplished during, attempts towards the synthesis one of its derivatives called anthralin (1,8-dihydroxy-9-anthrone) which is known as an antipsoriasis drug since 1916 [1]. this work is a new reigiospecilic preparation of 1,5-dha based on friedel-crafts reaction starting from 1,4-dimethoxybenzene. this synthetic route, in a...

Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3', 5- dihydroxy- 4', 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3',4', 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (β- sitosterol 3-O- β- D- glucopyranosid...

BACKGROUND Glycosmis is a genus of evergreen glabrous shrub and distributed all over India. It possesses various medicinal properties and is used in indigenous medicine for cough, rheumatism, anemia, and jaundice. Glycosmis arborea is a rich source of alkaloids, terpenoids, coumarins, as well as flavonoids. RESULTS The chemical investigation of methanol fraction of the leaves of G. arborea le...

Severe acute respiratory syndrome coronavirus 2 and associated disease 2019 is a newly identified human has imposed serious threat to global health. The rapid transmission of severe its ability spread in humans have prompted the development new approaches for treatment. requires RNA-dependent RNA polymerases life cycle propagation Spike (S)-protein attachment host cell surface receptors. virus ...

Dissolved organic matter (DOM) is a complex mixture of naturally occurring molecules originating from multiple marine and terrestrial sources. DOM plays significant role in water quality by affecting the photochemistry, trace metal transport, acidity aquatic systems. Understanding chemical composition helps interpret links between its optical properties molecular structures. Currently, origins ...

BACKGROUND/AIM Phenolic compounds isolated from Dendrobium ellipsophyllum Tang & Wang (Orchidaceae) have been shown to possess potential pharmacological activity; however, their anticancer as well as anti-metastasis activities are largely unknown. The aim of the present study was to isolate active compounds from D. ellipsophyllum and to explore the possible effects of phenolic compounds isolate...

The genus Salvia is a valuable origin of structurally diverse terpenoids. In a project directed at structurally interesting bioactive metabolites from Iranian Salvia species, we studied Salvia reuterana. Two new labdane diterpene, 6β,14α-dihydroxy-15-acetoxysclareol (1), and 14α,15- dihydroxy sclareol (2), were isolated from the aerial part of the plant. Their structures were established mainly...

an efficient synthesis of the 1,l'-dihydroxy-2,2'-(thiodimethy1ene)bis-9(10h)- anthrone (5) is described. reaction of 1 -methoxy-2-(bromomethy1)-9,loanthraquinone (1) with excess sodium sulfide in ethanol, demethylation to the corresponding hydroxy and subsequent selective reduction produced the title compound in high yield.

Palladium-catalyzed oxidative annulations between phenols and alkenylcarboxylic acids produced a library of benzofuran compounds. Depending on the nature of the substitution of the phenol precursor, either 2,3-dialkylbenzofurans or 2-alkyl-3-methylene-2,3-dihydrobenzofurans can be synthesized with excellent regioselectivity. Reactions between conjugated 5-phenylpenta-2,4-dienoic acids and pheno...