We have determined the three-dimensional (3D) structure of DNA duplex that includes tandem Hg(II)-mediated T-T base pairs (thymine-Hg(II)-thymine, T-Hg(II)-T) with NMR spectroscopy in solution. This is the first 3D structure of metallo-DNA (covalently metallated DNA) composed exclusively of 'NATURAL' bases. The T-Hg(II)-T base pairs whose chemical structure was determined with the (15)N NMR spe...

We propose a robust method for estimating dynamic 3D curvilinear branching structure from monocular images. While 3D reconstruction from images has been widely studied, estimating thin structure has received less attention. This problem becomes more challenging in the presence of camera error, scene motion, and a constraint that curves are attached in a branching structure. We propose a new gen...

our study performed upon an extended series of 28 compounds of 1,2,4-triazole derivativesthat demonstrate substantial in vitro antimicrobial activities by serial plate dilution method,using quantitative structure-activity relationship (qsar) methods that imply analysis ofcorrelations and multiple linear regression (mlr); a significant collection of moleculardescriptors was used e.g., edge adjac...

RNAComposer is a fully automated, web-interfaced system for RNA 3D structure prediction, freely available at http://rnacomposer.cs.put.poznan.pl/ and http://rnacomposer.ibch.poznan.pl/. Its main components are: manually curated database of RNA 3D structure elements, highly efficient computational engine and user-friendly web application. In this paper, we demonstrate how the latest additions to...

A new insulated gate bipolar transistor structure, the 3D-IGBT, is presented. The 3D-IGBT utilizes selective epitaxial silicon to form a top contacted anode and still retain the cellular structure of vemcally oriented devices. The 3D-IGBT , unlike other fully integrable power devices, exploits the merits of cellular structure to increase its packing density and thus reduce its on-resistance per...

[Pb(gly)2]n (1) (gly is the abbreviation of Glycine) have been synthesized and characterized by elemental analyses, IR, 1H NMR and 13C NMR spectroscopy. The single crystal structure of 1 show the complex is 2D coordination polymer with octahedral environment that is formed into 3D supramolecule through hydrogen bond. Structural determination of compound 1 reveals the Pb(II) ion is four coordina...

3D Continuum radiative transfer in complex dust configurations around young stellar objects and active nuclei II. 3D Structure of the dense molecular cloud core ρ Oph D Abstract. Constraints on the density and thermal 3D structure of the dense molecular cloud core ρ Oph D are derived from a detailed 3D radiative transfer modeling. Two ISOCAM images at 7 and 15 µm are fitted simultaneously by re...

The function of a protein generally is determined by its three-dimensional (3D) structure. Thus, it would be useful to know the 3D structure of the thousands of protein sequences that are emerging from the many genome projects. To this end, fold assignment, comparative protein structure modeling, and model evaluation were automated completely. As an illustration, the method was applied to the p...

The rich indigenous and endemic plants in Taiwan serve as a resourceful bank for biologically active phytochemicals. Based on our TIPdb database curating bioactive phytochemicals from Taiwan indigenous plants, this study presents a three-dimensional (3D) chemical structure database named TIPdb-3D to support the discovery of novel pharmacologically active compounds. The Merck Molecular Force Fie...