26 Objective: To evaluate changes in the peripheral refraction (PR), visual quality, and 27 accommodative lag (LAG) with a novel soft radial refractive gradient (SRRG) 28 experimental contact lens that produces peripheral myopic defocus. 29 Methods: Fifty-nine myopic right eyes were fitted with the lens. The PR was measured 30 up to 30 degrees in the nasal and temporal horizontal visual fields ...

Venerando et al reported an increased quantity of sialic acid at the surface of erythrocytes in diabetic patients and associated the increase with decreased activity of neutral sialidase, an enzyme for which they had previously demonstrated a role in physiologic desialylation of red cells.1 In their discussion they hypothesized that this excess in sialic acid was responsible for a shorter life ...

Given a set of n points (sites) inside a rectangle R and n points (label locations or ports) on its boundary, a boundary labeling problem seeks ways of connecting every site to a distinct port while achieving different labeling aesthetics. We examine the scenario when the connecting lines (leaders) are drawn as axis-aligned polylines with few bends, every leader lies strictly inside R, no two l...