The communication overhead is a major bottleneck for the execution of a process graph on a parallel computer system. In the case of two processors, the minimization of the communication can be modeled by the graph bisection problem. The spectral lower bound of 2jV j 4 for the bisection width of a graph is well-known. The bisection width is equal to 2jV j 4 iff all vertices are incident to 2 2 c...

The mechanism of action of 4'-demethylepipodophyllotoxin-9-(4,6-O-ethylidene-beta-D-glucopyra noside) (VP-16), an important antitumor agent, is unclear. There is evidence that DNA may be the target of action because VP-16 causes single-strand and double-strand breaks in DNA and produces cytotoxicity over a similar dose range. We have hypothesized that an enzyme system, such as dehydrogenase, ca...

In zebrafish embryos, the axons of the posterior trigeminal (Vp) and facial (VII) motoneurons project stereotypically to a small number of target muscles derived from the first and second branchial arches (BA1, BA2). Use of the Islet1 (Isl1)-GFP transgenic line enabled precise real-time observations of the growth cone behaviour of the Vp and VII motoneurons within BA1 and BA2. Screening for N-e...

Variegate porphyria (VP) is characterized by photocutaneous lesions and acute neuropsychiatric attacks. Decreased protoporphyrinogen oxidase activity results in accumulation of protoporphyrin (ogen) IX and coproporphyrin (ogen) III. During acute attacks delta-aminolevulinic acid and porphobilinogen also increase, suggesting that porphobilinogen deaminase (PBG-D) may be rate limiting. We have ex...

Bladder migration and transurethral extrusion is an extremely rare complication of ventriculoperitoneal (VP) shunt. Only eight cases have been reported in the English literature since 1995. We report a case of a 4-year-old boy with cerebral palsy, hydrocephalus, and VP shunted on both sides who presented with a protruded distal VP shunt from his urethral orifice. The patient was reported for ha...

Citation: Lima SA, Guerra-Duarte C, Costal-Oliveira F, Mendes TM, Figueiredo LFM, Oliveira D, Machado de Avila RA, Ferrer VP, Trevisan-Silva D, Veiga SS, Minozzo JC, Kalapothakis E and Chávez-Olórtegui C (2018) Recombinant Protein Containing B-Cell Epitopes of Different Loxosceles Spider Toxins Generates Neutralizing Antibodies in Immunized Rabbits. Front. Immunol. 9:653. doi: 10.3389/fimmu.201...

The charmless decay processes of $X(3872)$ provide us a good platform to study the nature and mechanism $X(3872)$. Based on molecular as $\overline{D}{D}^{*}$ bound state, we have investigated decays $X(3872)\ensuremath{\rightarrow}VV$ $VP$ via intermediate ${D}^{*}\overline{D}+\mathrm{c}.\mathrm{c}.$ meson loops, where $V$ $P$ stand for light vector pseudoscalar mesons, respectively. We discus...

BACKGROUND Replication-competent virus vector vaccines might have advantages compared with non-replicating vector vaccines. We tested the safety and immunogenicity of an oral adenovirus serotype 4 vector vaccine candidate (Ad4-H5-Vtn) expressing the haemagglutinin from an avian influenza A H5N1 virus. METHODS We did this phase 1 study at four sites in the USA. We used a computer-generated ran...

1 Research Branch, BC Ministry of Forests and Range, Kalamalka Forestry Centre, 3401 Reservoir Road, Vernon, British Columbia, Canada, V2B 2C7; 2 College of Science and Management, University of Northern British Columbia, 3333 University Way, Prince George, British Columbia, Canada V2N 4Z9; 3 Centre for Forest Conservation Genetics, Department of Forest Sciences, University of British Columbia,...