Significance of microRNAs (miRs), small non-coding molecules, has been implicated in a variety of biological processes. Here, we recruited retroviral insertional mutagenesis to obtain induction of an arbitrary noncoding RNAs, and coupled it with a cell based loss-of-function (5-Aza-2'-deoxycytidine (5Aza-dC)-induced senescence bypass) screening system. Cells that escaped 5-Aza-dC-induced senesc...

Mutations in the thymidine kinase (TK) gene of herpes simplex virus (HSV) have been associated with resistance to acyclovir (ACY) and possible recognition of neurotropic strains. We sequenced a 335-bp segment of the TK gene to determine the frequency of mutations in HSV strains recovered from dermal, genital, and cerebrospinal fluid (CSF) specimens (n = 200; 102 HSV type 1 [HSV-1] 98 HSV-2 stra...

while true do (noncritB; flagB := true; turn := A; waitfor (flagA = false) ∨ (turn = B); critB ; flagB := false) . A global state of our system S = A‖B (processes A,B running in parallel; they communicate by shared variables) can be described by the values of a few (boolean) variables, i.e., by a (column) vector from {0, 1} for some fixed k. Our system S thus determines (can be equated with) a ...

One of the major drawbacks of the symmetric QR algorithm is that it is not parallelizable. Each orthogonal similarity transformation that is needed to reduce the original matrix A to diagonal form is dependent upon the previous one. In view of the evolution of parallel architectures, it is therefore worthwhile to consider whether there are alternative approaches to reducing an n × n symmetric m...

The structural and electronic properties of gold decorated Si(335) surface are studied by means of density-functional calculations. The resulting structural model indicates that the Au atoms substitute some of the Si atoms in the middle of the terrace in the surface layer. Calculated electronic band structure near the Fermi energy features two metallic bands, one coming from the step edge Si at...

We report on a 151-ks net exposure Suzaku observation of the narrow-line Seyfert 1 galaxy Mrk 335. The 0.5–40 keV spectrum contains a broad Fe line, a strong soft excess below about 2 keV and a Compton hump around 20–30 keV. We find that a model consisting of a power law and two reflectors provides the best fit to the time-averaged spectrum. In this model, an ionized, heavily blurred, inner ref...

One hundred and twenty-one strains of ballistoconidiogenous yeasts were isolated from plant materials collected in Cuc Phuong National Park of Ninh Binh Province, Vietnam. Eighty-five strains selected for the morphology of their ballistoconidia and colony appearances were assigned to four genera: Bullera (39 strains), Kockovaella (5 strains), Sporobolomyces (39 strains) and Tilletiopsis (2 stra...

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Analysis of plasma microRNAs (miRNAs) by quantitative polymerase chain reaction (qPCR) provides a potential approach for cancer diagnosis. However, absolutely quantifying low abundant plasma miRNAs is challenging with qPCR. Digital PCR offers a unique means for assessment of nucleic acids presenting at low levels in plasma. This study aimed to evaluate the efficacy of digital PCR for quantifica...

Fermentation is one of the industrially important processes for the development of microbial metabolites that has immense applications in various fields. This has prompted to employ fermentation as a major technique in the production of phytase from microbial source. In this study, a comparison was made between submerged (SmF) and solid-state fermentations (SSF) for the production of phytase fr...